HIV Flashcards

1
Q

What are major risk factors for transmission, less common risk factors

A

MSM, intravenous drug use, heterosexual contact, occupation exposure/ vertical transmission, blood transfusions

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2
Q

What body fluids infected with the virus

A

blood, semen, vaginal fluids, breast milk

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3
Q

T/F: HIV is NOT transmitted through kissing, tears, sharing eating utensils, toilet seats, insects

A

True

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4
Q

What are the two parameters that should be monitored if a person has HIV

A

Viral load and CDC count

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5
Q

T/F: HIV screening should be for all people aged 13-64 years old as part of routine health care

A

True

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6
Q

T/F: Males usually get HIV from MSM contact while females usually get HIV from heterosexual sex

A

True

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7
Q

What is used to diagnose HIV, how many viral replication happens in a day

A

Antibodies, 10^12

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8
Q

What is the definition of HIV, what is the definition of AIDS

A

screening test and conformatory test are both positive, person testing HIV positive AND CD4 less than 200 or diagnosed with one or more AIDS defining illnesses

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9
Q

What are the AIDS defining ilnesses

A

Pneumocystis carinii penumonia (PCP/PJP), Systemic Candidiasis, cryptococcal meningitis

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10
Q

What is the primary reason for HIV treatment failure

A

Low adherence

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11
Q

What are the predictors or poor adhearnace

A

Lack of education, active alchol and drug use, health insurance, pill burden, drug side effects, unstable living situation, lack of belief

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12
Q

What is the primary goal of HIV treatment, secondary goal

A

improve and preserve immune function and reduce HIV-associated morbidity/mortality/ reduce HIV transmission

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13
Q

What are the NRTIs

A

Abacavir, Emtricitabine, Lamivudine, TAF, TDF

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14
Q

Whart are the intergrase inhibitors, protease inhibitors, what boosting agents

A

Raltegravir, Dolutegravir, Elvitegravir/ Atazanavir and Darunavir, Ritonavir (Norvir) and Cobicstat

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15
Q

What is the most common opportunistic infection that has a diffuse infiltrates all over the lungs

A

PJP/PCP

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16
Q

What is the preferred treatment for PJP, what are the alternatives

A

Bactrim DS 15 mg/kg/day dosed by TMP po TID for 21 DAYS/ Primaquine 30 mg every day PLUS Clindamycin 300-450 TID or QID, Atovaquone suspension 750 mg BID

17
Q

What is a severe symptom of PJP, what else would be given if this is present, what is the schedule

A

Hpoxemia, if pO2 is less than 70 mmHg then prednisone is recommended, 40 mg BID for 5 days then 40 mg every day 5 days, then 20 mg every day for 11 days

18
Q

What drug can be given IV if by mouth is not available for PJP

A

Penamidine 3-4 mg/kg/day