[HISTO] CEREBELLUM Flashcards

1
Q

gray matter includes

A

outer cortex
4 pairs of cerebellar nuclei

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2
Q

white matter includes

A

afferents
efferents

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3
Q

each folium contains

A

white matter core
grey matter covering

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4
Q

layers of cerebellar cortex

A

molecular layer
purkinje layer
granular layer

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5
Q

outermost layer

A

molecular layer

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6
Q

middle layer

A

purkinje layer

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7
Q

innermost layer

A

granular layer

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8
Q

outer stellate cells

A

~found in: superficial part of molecular layer
~small cell bodies
~short dendrites in same layer
~axons parallel to cerebellum surface
~synapse w/ purkinje dendrites

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9
Q

basket cells

A

~found deep in molecular layer
~dendrites in same layer
~axons=basket arborizations around purkinje cell bodies
~synapse w/ 10 Purkinje cells

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10
Q

fibers found in molecular layer (6)

A

1-dendritic arborizations + axons
2-Climbing fibers
3-Purkinje dendrites
4-Purkinje axons
5-axons of granule cells
6-dendrites of Golgi type II cells

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11
Q

Purkinje cells

A

~large pyriform flask cell body
~vesicular central nucleus
~coarse cytoplasmic Nissl’s granules
~dendritic tree give 1ry,2ry & 3ry branches
~axons=myelinated
~synapse w/ deep cerebellar nuclei
~efferent pathway

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12
Q

which cell’s axons synapse w/ deep cerebellar nuclei

A

purkinje

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13
Q

cells w/ myelinated axons

A

Purkinje

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14
Q

cells w/ unmyelinated axons

A

granular
olivocerebellar fibers

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15
Q

granule cells

A

~small
~large rounded nucleus
~thin cytoplasm
~few Nissl’s granules
~unmyelinated axon
~dendrites= claw like=terminate in glomerulus
~axons bifurcate to give parallel fibers
~synapse w/ purkinje dendrites

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16
Q

cells which synapse w/ dendrites of Purkinje fibers

A

outer stellate cells
basket cells
granule cells

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17
Q

parallel fibers originate from?

A

granule cells’ axons

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18
Q

golgi type II cells

A

dendrites extend in all layers of cortex
axons end in glomerulus

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19
Q

cerebellar islands/glomeruli

A

irregularly dispersed pale non cellular areas

20
Q

synaptic structure of cerebellar islands

A

1-mossy fibers terminals
2- dendrites of granule cells
3-axons of golgi II

21
Q

function of cerebellar islands

A

excite granule cells which (+) purkinje fibers

22
Q

the only excitatory neuron of the cerebellar cortex

A

granule cells

23
Q

only efferent pathway of the cerebellar cortex

A

Purkinje cell axons

24
Q

purkinje cell axons effect on cerebellar nuclei

A

inhibitory

25
Purkinje cells receive which fibers?
climbing fibers mossy fibers
26
structure responsible for sending efferents from the cerebellar cortex
deep cerebellar nuclei
27
all Purkinje fibers discharge to cerebellar nuclei EXCEPT IN?
flocculonodular lobe they discharge directly to vestibular nuclei
28
afferent fibers
Climbing fibers mossy fibers
29
afferent fibers enter cerebellar cortex via
ICP MCP
30
climbing fibers
olivocerebellar fibers nonmyelinated climb smooth dendritic branches of purkinje cells
31
stimulation of climbing fibers leads to
Purkinje cells stimulation
32
mossy fibers (6)
(all except olivocerebellar) 1-ventral external arcuate 2-Vestibulo-cerebellar tract 3-reticulo-cerebellar tract 4-Ponto-cerebellar tract 5- spinocerebellar tracts 6-Cuneocerebellar tracts
33
role of mossy fibers
enter granular layer & give collaterals + rosettes
34
rosettes
fine lobulated enlargements. form center of glomeruli
35
Purkinje cells project efferent fibers to
deep cerebellar nuclei vestibular nuclei
36
deep cerebellar nuclei (4)
dentate emboliform globose fastigial
37
wedge shaped cell mass medial to dentate nucleus
emboliform
38
rounded cell group medial to emboliform nucleus
globose
39
largest nucleus convoluted mass of gray matter w/ hilus directed medially
dentate
40
most medial nucleus
fastigial
41
corticonuclear projections are projected:
from purkinje cells to deep cerebellar nuclei
42
most corticonuclear projections are projected to
fastigial nucleus
43
fastigial nucleus projects corticonuclear projections to?
1-vestibular nuclei= vestibulospinal tract 2-RF= reticulospinal tract
44
dentate, emboliform & globose nuclei project corticonuclear projections to:
1-red nucleus= rubrospinal tract 2-VLN of thalamus= thalamo-cortical tract
45
overall function of deep cerebellar nuclei
regulation of muscle tone & movement coordination
46
extracerebellar inputs come from
pontine nuclei & inf. olivary nucleus TO--->dentate
47
which nucleus receives extracerebellar inputs?
dentate