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CNS > [HISTO] CEREBELLUM > Flashcards

[HISTO] CEREBELLUM Flashcards

1
Q

gray matter includes

A

outer cortex
4 pairs of cerebellar nuclei

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2
Q

white matter includes

A

afferents
efferents

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3
Q

each folium contains

A

white matter core
grey matter covering

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4
Q

layers of cerebellar cortex

A

molecular layer
purkinje layer
granular layer

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5
Q

outermost layer

A

molecular layer

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6
Q

middle layer

A

purkinje layer

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7
Q

innermost layer

A

granular layer

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8
Q

outer stellate cells

A

~found in: superficial part of molecular layer
~small cell bodies
~short dendrites in same layer
~axons parallel to cerebellum surface
~synapse w/ purkinje dendrites

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9
Q

basket cells

A

~found deep in molecular layer
~dendrites in same layer
~axons=basket arborizations around purkinje cell bodies
~synapse w/ 10 Purkinje cells

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10
Q

fibers found in molecular layer (6)

A

1-dendritic arborizations + axons
2-Climbing fibers
3-Purkinje dendrites
4-Purkinje axons
5-axons of granule cells
6-dendrites of Golgi type II cells

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11
Q

Purkinje cells

A

~large pyriform flask cell body
~vesicular central nucleus
~coarse cytoplasmic Nissl’s granules
~dendritic tree give 1ry,2ry & 3ry branches
~axons=myelinated
~synapse w/ deep cerebellar nuclei
~efferent pathway

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12
Q

which cell’s axons synapse w/ deep cerebellar nuclei

A

purkinje

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13
Q

cells w/ myelinated axons

A

Purkinje

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14
Q

cells w/ unmyelinated axons

A

granular
olivocerebellar fibers

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15
Q

granule cells

A

~small
~large rounded nucleus
~thin cytoplasm
~few Nissl’s granules
~unmyelinated axon
~dendrites= claw like=terminate in glomerulus
~axons bifurcate to give parallel fibers
~synapse w/ purkinje dendrites

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16
Q

cells which synapse w/ dendrites of Purkinje fibers

A

outer stellate cells
basket cells
granule cells

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17
Q

parallel fibers originate from?

A

granule cells’ axons

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18
Q

golgi type II cells

A

dendrites extend in all layers of cortex
axons end in glomerulus

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19
Q

cerebellar islands/glomeruli

A

irregularly dispersed pale non cellular areas

20
Q

synaptic structure of cerebellar islands

A

1-mossy fibers terminals
2- dendrites of granule cells
3-axons of golgi II

21
Q

function of cerebellar islands

A

excite granule cells which (+) purkinje fibers

22
Q

the only excitatory neuron of the cerebellar cortex

A

granule cells

23
Q

only efferent pathway of the cerebellar cortex

A

Purkinje cell axons

24
Q

purkinje cell axons effect on cerebellar nuclei

A

inhibitory

25
Q

Purkinje cells receive which fibers?

A

climbing fibers
mossy fibers

26
Q

structure responsible for sending efferents from the cerebellar cortex

A

deep cerebellar nuclei

27
Q

all Purkinje fibers discharge to cerebellar nuclei EXCEPT IN?

A

flocculonodular lobe
they discharge directly to vestibular nuclei

28
Q

afferent fibers

A

Climbing fibers
mossy fibers

29
Q

afferent fibers enter cerebellar cortex via

A

ICP
MCP

30
Q

climbing fibers

A

olivocerebellar fibers
nonmyelinated
climb smooth dendritic branches of purkinje cells

31
Q

stimulation of climbing fibers leads to

A

Purkinje cells stimulation

32
Q

mossy fibers (6)

A

(all except olivocerebellar)
1-ventral external arcuate
2-Vestibulo-cerebellar tract
3-reticulo-cerebellar tract
4-Ponto-cerebellar tract
5- spinocerebellar tracts
6-Cuneocerebellar tracts

33
Q

role of mossy fibers

A

enter granular layer & give collaterals + rosettes

34
Q

rosettes

A

fine lobulated enlargements.
form center of glomeruli

35
Q

Purkinje cells project efferent fibers to

A

deep cerebellar nuclei
vestibular nuclei

36
Q

deep cerebellar nuclei (4)

A

dentate
emboliform
globose
fastigial

37
Q

wedge shaped cell mass medial to dentate nucleus

A

emboliform

38
Q

rounded cell group medial to emboliform nucleus

A

globose

39
Q

largest nucleus
convoluted mass of gray matter w/ hilus directed medially

A

dentate

40
Q

most medial nucleus

A

fastigial

41
Q

corticonuclear projections are projected:

A

from purkinje cells to deep cerebellar nuclei

42
Q

most corticonuclear projections are projected to

A

fastigial nucleus

43
Q

fastigial nucleus projects corticonuclear projections to?

A

1-vestibular nuclei= vestibulospinal tract

2-RF= reticulospinal tract

44
Q

dentate, emboliform & globose nuclei project corticonuclear projections to:

A

1-red nucleus= rubrospinal tract
2-VLN of thalamus= thalamo-cortical tract

45
Q

overall function of deep cerebellar nuclei

A

regulation of muscle tone &
movement coordination

46
Q

extracerebellar inputs come from

A

pontine nuclei &
inf. olivary nucleus
TO—>dentate

47
Q

which nucleus receives extracerebellar inputs?

A

dentate

CNS (29 decks)

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