Hepatitis Flashcards

2
Q

Best markers for current acute HBV infection

A

IgM anti-HBc & HBsAg

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3
Q

Best markers for past HBV infection

A

IgG anti-HBs & IgG anti-HBc In the absence of HBsAg

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4
Q

What markers will be present in an HBV vaccinated individual

A

IgG anti-HBs but no anti-HBc

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5
Q

Best marker for chronic HBV infection

A

HBsAg longer than 6 months but no anti-HBs

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6
Q

Best markers for HBV infectivity

A

HBV DNA or HBeAg

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7
Q
Diagnose: 
HBsAg: +
Anti-HBs: -
HBeAg: +
Anti-HBe: -
Anti-HBc: IgM
A

Acute HBV

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8
Q
Diagnose:
HBsAg: -
Anti-HBs: -
HBeAg: -
Anti-HBe: +
Anti-HBc: IgM
A

HBV Window Period

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9
Q
Diagnose:
HBsAg: +
Anti-HBs: -
HBeAg: +
Anti-HBe: -
Anti-HBc: IgG
A

High infectivity Chronic HBV

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10
Q
Diagnose:
HBsAg: +
Anti-HBs: -
HBeAg: -
Anti-HBe: +
Anti-HBc: IgG
A

Low infectivity Chronic HBV

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11
Q
Diagnose:
HBsAg: -
Anti-HBs: +
HBeAg: -
Anti-HBe: +
Anti-HBc: IgG
A

Recovery from HBV infection

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12
Q
Diagnose:
HBsAg: -
Anti-HBs: +
HBeAg: -
Anti-HBe: -
Anti-HBc: -
A

Immunized against HBV

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13
Q

This Hepatitis virus is a Picornavirus

A

HAV

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14
Q

This Hepatitis virus is a Hepadnavirus

A

HBV

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15
Q

This Hepatitis virus is a Flavivirus

A

HCV

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16
Q

This Hepatitis virus is a Delta Virus

A

HDV

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17
Q

This Hepatitis virus is a Hepevirus

A

HEV

18
Q

Which Hepatitis virus requires infection with which other hepatitis virus

A

HDV requires HBV infection

19
Q

Which Hepatitis viruses carry a risk of Hepatocellular Carcinoma

A

HBV, HCV, & HDV

20
Q

Which Hepatitis viruses are transmitted by blood or sexual contact

A

HBV, HCV, & HDV

21
Q

Which Hepatitis viruses are transmitted by fecal oral route

A

HAV & HEV

22
Q

Which Hepatitis viruses are naked viruses

A

HAV & HEV

23
Q

When does a Hepatitis superinfection occur

A

When an HBV infected individual is infected with HDV

24
Q

What is the standard treatment option for HBV & HCV

A

Alpha-interferon + Ribovirin

25
Q

What percent of symptomatic HBV infected individuals develop acute vs chronic disease

A

Acute: 90% Chronic: 10%

26
Q

What percent of symptomatic HCV infected individuals develop acute vs chronic disease

A

Acute: 20% Chronic: 80%

27
Q

Which Hepatitis Virus causes high mortality in pregnant women

A

HEV

28
Q

How do liver enzymes ALT and AST compare in viral hepatitis

A

ALT > AST

29
Q

How do liver enzymes ALT and AST compare in alcoholic hepatitis

A

AST > ALT

30
Q

IgM Anti-HAV Indicates what

A

Active HAV infection

31
Q

IgG Anti-HAV indicates what

A

Prior HAV infection and/or HAV vaccination