Amino Acid Derivatives Flashcards
Phenylalanine makes
Tyrosine -> Dopa -> Dopamine-> Norepinephrine-> Epinephrine
Tyrosine + Iodine =
Thyroxine
Dopa can convert to:
Melanin
Phenylalanine -> Tyronsine: enzyme & cofactor?
Phenylalanine Hydroxylase & cofactor tetrahydrabiopterin
PKU is a deficiency of what enzyme?
Phenylalaine Hydroxylase
Tyrosine -> Dopa: enzyme?
Tyrosine Hydroxylase
Dopa -> Dopamine (enzyme?)
Dopa decarboxylase
2 products from Tryptophan
Niacin & Serotonin
Tryptophan -> Niacin -> ?? (also what vitamin is needed for Trp to niacin)
NAD/NADP; B6 is needed
Trp -> Serotonin -> ?? (also, what cofactor is needed to get from Trp to serotonin)
Melatonin; BH4
Histidine -> ?? (also what vitamin is needed)
Histamine; need B6
What gland makes melatonin
pineal gland
Glycine + cofactor (1) -> (2) -> (3)
1: B6; 2: porphyrin; 3: Heme
Porphyrin -> Heme (enzyme?)
Aminolevulinate Synthase
Arginine makes what 3 things?
- Creatine, 2. Urea, 3. Nitric Oxide
Glutamate & what vitamin is essential for ?
Glutamate + B6 -> GABA
Creatinine
Arginine
Urea comes from
Arginine
Nitric oxide comes from
Arginine
Porphyrin comes from
Glycine (B6)
Heme comes from
Glycine-> Porphyrin
Glutamate makes
Glutathione
Glutathione come from
Glutamate
Gaba comes from
Glutamate + B6
Histamine comes from
Histidine + B6
NAD/NADP comes from what amino acid?
Tryptophan
Melatonin come froms what amino acid?
Tryptophan