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High Yield > First Aid Drug reactions > Flashcards

First Aid Drug reactions Flashcards

1
Q

Coronary vasospasm

A

Sumatriptan, cocaine

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2
Q

Cutaneous flushing

A

Vancomycin, adenosine, niacin, calcium channel blockers

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3
Q

Dilated cardiomyopathy

A

Doxorubicin, daunorubicin

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4
Q

Torsades de pointes

A

Class IA (quinidine) and Class III (sotalol) antiarrhythmics

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5
Q

Agranulocytosis

A

Carbamazepine, clozapine, colchicine, propylthiouracil, methimazole, dapsone, ticlopidine (neutropenia)

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6
Q

Aplastic anemia

A

Chloramphenicol, benzene, NSAIDs, propylthiouracil, methimazole

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7
Q

Direct Coombs-positive hemolytic anemia

A

Methyldopa

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8
Q

Gray baby syndrome

A

Chloramphenicol

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9
Q

Hemolysis in G6PD patients

A

Sulfonamides, nitrofurantoin, isoniazid, primaquine, aspirin, ibuprofen

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10
Q

Megaloblastic anemia

A

Phenytoin, methotrexate, sulfa drugs

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11
Q

Thrombotic complications

A

OCPs

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12
Q

Cough

A

ACE inhibitors

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13
Q

Pulmonary fibrosis

A

Bleomycin, amiodarone, busulfan

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14
Q

Acute cholestatic hepatitis

A

Macrolides

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15
Q

Focal to massive hepatic necrosis

A

Acetominophen, halothane, vaproic acid, amanita phalloides (death cap mushroom)

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16
Q

Hepatitis

A

Isoniazid, statins

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17
Q

Pseudomembranous colitis

A

Ampicillin, clindamycin

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18
Q

Adrenocorticol insufficiency

A

Glucocorticoid withdrawal

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19
Q

Gynecomastia

A

Ketoconazole, spironolactone, eplerenone, digitalis, cimetidine, chronic alcohol use, estrogens

20
Q

Hot flashes

A

Tamoxifen, clomiphene

21
Q

Hypothyroidism

A

Amiodarone, sulfonamides, lithium

22
Q

Hyperglycemia

A

Thiazides, niacin, tacrolimus, protease inhibitors

23
Q

Fat redistribution

A

Glucocorticoids, protease inhibitors

24
Q

Gingival hyperplasia

A

Verapamil, phenytoin

25
Q

Gout

A

Furosemide, thiazides, niacin, cyclosporine, pyrazinamide, low dose salicylates

26
Q

Myopathies

A

Fibrates, niacin, colchicine, hydroxychlorquine, interferon alpha, penicillamine, statins, glucocorticoids

27
Q

Osteoporosis

A

Corticosteroids, heparin

28
Q

Photosensitivity

A

Sulfonamides, amiodarone, tetracycline

29
Q

Rash (Stevens-Johnson Syndrome)

A

Penicillin, sulfa drugs, allopurinol, ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital

30
Q

SLE-like syndrome

A

Hydralazine, isoniazid, procainamide, phenytoin

31
Q

Tendonitis, tendon rupture, and cartilage damage (kids)

A

Fluoroquinolones

32
Q

Diabetes insipidus

A

Lithium, demeclocycline

33
Q

Fanconi’s syndrome

A

Expired tetracycline

34
Q

Interstitial nephritis

A

NSAIDs, methicillin, furosemide

35
Q

Hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide (prevent by administering with mesna)

36
Q

SIADH

A

Carbamazepine, cyclophosphamide

37
Q

Cinchonism

A

Quinidine, quinine

38
Q

Parkinson-like syndrome

A

Haloperidol, -azines (antipsychotics), reserpine, metoclopromide

39
Q

Seizures

A

Bupropion, imipenem/cilastatin, isoniazid

40
Q

Tardive dyskinesia

A

Antipsychotics

41
Q

Antimuscarinic

A

Atropine, TCAs, H1 blockers, neuroleptics (antipsychotics and atypical antipsychotics), digoxin

42
Q

Disulfiram-like reaction

A

Metronidazole, cephalosporins, procarbazine, 1st-generation sulfonylureas

43
Q

Nephrotoxicity/ototoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin

44
Q

p450 inducers

A

St. Johns wort, quinidine*, carbamazepine, griseofulvin, chronic EtOH abuse, rifampin, barbiturates, phenytoin

45
Q

p450 inhibitors

A

Macrolides, amiodarone, grapefruit juice, isoniazid, cimetidine, ritonavir, acute EtOH abuse, ciprofloxacin, ketoconzaole, sulfonamides

46
Q

Sulfa drug allergies (fever, urinary tract infection, pruritic rash, Stevens-Johnsons syndrome, hemolytic anemia, thrombocytopenia, agranulocytosis, and urticaria)

A

Probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamide antibiotics, sulfonylureas, sulfasalazine

High Yield (34 decks)

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