Hemoglobin Flashcards

1
Q

What are the two parts of hemoglobin?

A

Heme → iron
Globin → protein

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2
Q

What are the types of hemoglobin?

A

Hemoglobin A
Hemoglobin A2
Fetal hemoglobin

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3
Q

What is hemoglobin A?

A

The globin part is two a chains, each of which contains 141 amino acid residues and two B chains, each of which contains 146 amino aid residues

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4
Q

What is hemoglobin A2?

A

The B chains are replaced by sigma chains

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5
Q

What is fetal hemoglobin?

A

B chains are replaced by gama chains

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6
Q

What does reactions of hemoglobin include?

A

Oxyhemoglobin
Reduced hemoglobin
Methemoglobin
Carbon monoxyhemoglobein

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7
Q

What is methemoglobin?

A

When the ferrous iron is converted to ferric iron forming methemoglobin, which is dark-coloured

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8
Q

What causes dusky discoloration of the skin?

A

Methemoglobin present in large quantities in the circulation

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