Heme/Onc buzzwords Flashcards
largest WBC
monocyte
this wbc helps fight worm infections
Eosinophils
this wbc is associated with asthma and allergies
eosinophils
superficial bleeding under the skin + mucosal bleeding
low platelet count aka thrombocytopenia
PT=prolonged
PTT=prolonged
TT=normal
–single defects in coag cascade?
factor V
Factor X
prothrombin
PT=prolonged
PTT=normal
TT=normal
–single defects in coag cascade?
factor VII
PT=normal
PTT=prolonged
TT=normal
–single defects in coag cascade?
factors XII, XI, IX or VIII
PT=normal or prolonged
PTT=normal or prolonged
TT=prolonged
–single defects in coag cascade?
Fibrinogen or thrombin inhibitor
macro-ovalocyte RBCs
megaloblastic anemia
microcyte RBC
iron deficiency
Thalassemia
Pencil cell RBCs
iron def
tear drop RBCs
Myelofibrosis
extrameducally hemopoiesis
target cell RBCs
liver dz
hemoglobinopathies
post-splenectomy
howell-holly body RBCs
Nuclear inclusion
Post-splenectomy
Spherocyte RBCs
hereditaryy spherocytosis
atuoimmune hemolytic anemia
Stomatocyte RBCs
Liver dz
Fragmented RBCs
Microanglipathy HUS TTP Cardiac valvue DIC
Blister cell RBC
g6pd deficiency
spur cell RBCs
severe liver dz
Anisocytosis RBC
- define
- indicates?
variation in size of RBC
-can indicate anemia
Marcrocytosis RBC
- define
- inds
large RBCs
- vit b12 or folate def
- megaloblastic anemia—-pernicious anemia
- chronic ETOH
- liver dz
- thyroid dz
- myelodysplastic syndrome
Microcytosis RBC
- define
- indicate q
small RBCs
- iron deficiency anemia ***
- inherited disorder like Thalassemia
Poikilocytosis RBCs
-variation in shape of RBC
Acanthocytes RBCs
Spur or spiculated cells
- irreg shaped cells with 5-10 spicules
- splenectomy
- liver dz
- abetalipoproteineimia
Echinocytes RBCs
Burr or crenated
- 10-30 blunt projections
- renal failure
- or artifact—something caused during sample preparation
Elliptocytes RBCs
Ovalocytes
-elliptical-shaped RBCs seen in hereditary elliptocytosis and various anemias
Fragmented cells RBCs
- shistocytes
- helmet cells
- DIC
- hemolytic uremic syndrome
- thrombtic thrombocytopenia purpura
- vascular artificial devices —like mechnical heart valves
Rouleaux RBCs
-appear as a stack of coins or seen in ppl with multiple myelmoa or Waldenstrom macroglobulienemia due to incr serum proteins
crescent shaped RBCs
sickle cell
target cells RBCs
resemle a bull’s eye
- hemoglobinopathies
- thalasemia
- various anemias
- liver dz
Teardrop cells
dacrocytes
- RBCs tht resemble a teardrop
- myelofibrosis
- thalassemia
Spherocytes RBCs
hemolytic anemia
spherocytosis
Hypochromia/hypochromasia RBCs
- thalassemia
- iron def
- RBC pale in color due to insuff hgb
Hyperchromia/hyperchromasia RBCs
- darker in color due to greater than normal hgb
- dehydration
- spherocytes
Polychromasia
blue-staining RBCs reflecting increased RNA content
-immature cells due to early release from bone marro
reticulocyte RBCs
-incr number?
immature RBCs
- blue staining
- elevated=acute blood loss, hypoxia, rbc destruction, sickle cell, g6pd def, autoimmune hemolytic anemia
