Heme/Onc buzzwords Flashcards

1
Q

largest WBC

A

monocyte

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2
Q

this wbc helps fight worm infections

A

Eosinophils

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3
Q

this wbc is associated with asthma and allergies

A

eosinophils

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4
Q

superficial bleeding under the skin + mucosal bleeding

A

low platelet count aka thrombocytopenia

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5
Q

PT=prolonged
PTT=prolonged
TT=normal
–single defects in coag cascade?

A

factor V
Factor X
prothrombin

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6
Q

PT=prolonged
PTT=normal
TT=normal
–single defects in coag cascade?

A

factor VII

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7
Q

PT=normal
PTT=prolonged
TT=normal
–single defects in coag cascade?

A

factors XII, XI, IX or VIII

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8
Q

PT=normal or prolonged
PTT=normal or prolonged
TT=prolonged
–single defects in coag cascade?

A

Fibrinogen or thrombin inhibitor

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9
Q

macro-ovalocyte RBCs

A

megaloblastic anemia

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10
Q

microcyte RBC

A

iron deficiency

Thalassemia

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11
Q

Pencil cell RBCs

A

iron def

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12
Q

tear drop RBCs

A

Myelofibrosis

extrameducally hemopoiesis

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13
Q

target cell RBCs

A

liver dz
hemoglobinopathies
post-splenectomy

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14
Q

howell-holly body RBCs

A

Nuclear inclusion

Post-splenectomy

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15
Q

Spherocyte RBCs

A

hereditaryy spherocytosis

atuoimmune hemolytic anemia

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16
Q

Stomatocyte RBCs

17
Q

Fragmented RBCs

A
Microanglipathy 
HUS 
TTP 
Cardiac valvue 
DIC
18
Q

Blister cell RBC

A

g6pd deficiency

19
Q

spur cell RBCs

A

severe liver dz

20
Q

Anisocytosis RBC

  • define
  • indicates?
A

variation in size of RBC

-can indicate anemia

21
Q

Marcrocytosis RBC

  • define
  • inds
A

large RBCs

  • vit b12 or folate def
  • megaloblastic anemia—-pernicious anemia
  • chronic ETOH
  • liver dz
  • thyroid dz
  • myelodysplastic syndrome
22
Q

Microcytosis RBC

  • define
  • indicate q
A

small RBCs

  • iron deficiency anemia ***
  • inherited disorder like Thalassemia
23
Q

Poikilocytosis RBCs

A

-variation in shape of RBC

24
Q

Acanthocytes RBCs

A

Spur or spiculated cells

  • irreg shaped cells with 5-10 spicules
  • splenectomy
  • liver dz
  • abetalipoproteineimia
25
Echinocytes RBCs
Burr or crenated - 10-30 blunt projections - renal failure - or artifact---something caused during sample preparation
26
Elliptocytes RBCs
Ovalocytes | -elliptical-shaped RBCs seen in hereditary elliptocytosis and various anemias
27
Fragmented cells RBCs
- shistocytes - helmet cells * DIC * hemolytic uremic syndrome * thrombtic thrombocytopenia purpura * vascular artificial devices ---like mechnical heart valves
28
Rouleaux RBCs
-appear as a stack of coins or seen in ppl with multiple myelmoa or Waldenstrom macroglobulienemia due to incr serum proteins
29
crescent shaped RBCs
sickle cell
30
target cells RBCs
resemle a bull's eye - hemoglobinopathies - thalasemia - various anemias - liver dz
31
Teardrop cells
dacrocytes - RBCs tht resemble a teardrop - myelofibrosis - thalassemia
32
Spherocytes RBCs
hemolytic anemia | spherocytosis
33
Hypochromia/hypochromasia RBCs
- thalassemia - iron def - RBC pale in color due to insuff hgb
34
Hyperchromia/hyperchromasia RBCs
- darker in color due to greater than normal hgb - dehydration - spherocytes
35
Polychromasia
blue-staining RBCs reflecting increased RNA content | -immature cells due to early release from bone marro
36
reticulocyte RBCs | -incr number?
immature RBCs - blue staining - elevated=acute blood loss, hypoxia, rbc destruction, sickle cell, g6pd def, autoimmune hemolytic anemia