Heme/Onc buzzwords

Question 1

largest WBC

Answer 1

monocyte

Question 2

this wbc helps fight worm infections

Answer 2

Eosinophils

Question 3

this wbc is associated with asthma and allergies

Answer 3

eosinophils

Question 4

superficial bleeding under the skin + mucosal bleeding

Answer 4

low platelet count aka thrombocytopenia

Question 5

PT=prolonged
PTT=prolonged
TT=normal
–single defects in coag cascade?

Answer 5

factor V
Factor X
prothrombin

Question 6

PT=prolonged
PTT=normal
TT=normal
–single defects in coag cascade?

Answer 6

factor VII

Question 7

PT=normal
PTT=prolonged
TT=normal
–single defects in coag cascade?

Answer 7

factors XII, XI, IX or VIII

Question 8

PT=normal or prolonged
PTT=normal or prolonged
TT=prolonged
–single defects in coag cascade?

Answer 8

Fibrinogen or thrombin inhibitor

Question 9

macro-ovalocyte RBCs

Answer 9

megaloblastic anemia

Question 10

microcyte RBC

Answer 10

iron deficiency

Thalassemia

Question 11

Pencil cell RBCs

Answer 11

iron def

Question 12

tear drop RBCs

Answer 12

Myelofibrosis

extrameducally hemopoiesis

Question 13

target cell RBCs

Answer 13

liver dz
hemoglobinopathies
post-splenectomy

Question 14

howell-holly body RBCs

Answer 14

Nuclear inclusion

Post-splenectomy

Question 15

Spherocyte RBCs

Answer 15

hereditaryy spherocytosis

atuoimmune hemolytic anemia

Question 16

Stomatocyte RBCs

Answer 16

Liver dz

Question 17

Fragmented RBCs

Answer 17

Microanglipathy 
HUS 
TTP 
Cardiac valvue 
DIC

Question 18

Blister cell RBC

Answer 18

g6pd deficiency

Question 19

spur cell RBCs

Answer 19

severe liver dz

Question 20

Anisocytosis RBC

• define
• indicates?

Answer 20

variation in size of RBC

-can indicate anemia

Question 21

Marcrocytosis RBC

• define
• inds

Answer 21

large RBCs

• vit b12 or folate def
• megaloblastic anemia—-pernicious anemia
• chronic ETOH
• liver dz
• thyroid dz
• myelodysplastic syndrome

Question 22

Microcytosis RBC

• define
• indicate q

Answer 22

small RBCs

• iron deficiency anemia ***
• inherited disorder like Thalassemia

Question 23

Poikilocytosis RBCs

Answer 23

-variation in shape of RBC

Question 24

Acanthocytes RBCs

Answer 24

Spur or spiculated cells

• irreg shaped cells with 5-10 spicules
• splenectomy
• liver dz
• abetalipoproteineimia

Question 25

Echinocytes RBCs

Answer 25

Burr or crenated

• 10-30 blunt projections
• renal failure
• or artifact—something caused during sample preparation

Question 26

Elliptocytes RBCs

Answer 26

Ovalocytes

-elliptical-shaped RBCs seen in hereditary elliptocytosis and various anemias

Question 27

Fragmented cells RBCs

Answer 27

• shistocytes
• helmet cells
• DIC
• hemolytic uremic syndrome
• thrombtic thrombocytopenia purpura
• vascular artificial devices —like mechnical heart valves

Question 28

Rouleaux RBCs

Answer 28

-appear as a stack of coins or seen in ppl with multiple myelmoa or Waldenstrom macroglobulienemia due to incr serum proteins

Question 29

crescent shaped RBCs

Answer 29

sickle cell

Question 30

target cells RBCs

Answer 30

resemle a bull’s eye

• hemoglobinopathies
• thalasemia
• various anemias
• liver dz

Question 31

Teardrop cells

Answer 31

dacrocytes

• RBCs tht resemble a teardrop
• myelofibrosis
• thalassemia

Question 32

Spherocytes RBCs

Answer 32

hemolytic anemia

spherocytosis

Question 33

Hypochromia/hypochromasia RBCs

Answer 33

• thalassemia
• iron def
• RBC pale in color due to insuff hgb

Question 34

Hyperchromia/hyperchromasia RBCs

Answer 34

• darker in color due to greater than normal hgb
• dehydration
• spherocytes

Question 35

Polychromasia

Answer 35

blue-staining RBCs reflecting increased RNA content

-immature cells due to early release from bone marro

Question 36

reticulocyte RBCs

-incr number?

Answer 36

immature RBCs

• blue staining
• elevated=acute blood loss, hypoxia, rbc destruction, sickle cell, g6pd def, autoimmune hemolytic anemia