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PANRE > Heme > Flashcards

Heme Flashcards

1
Q

Best indicator for RBC loss?

A

reticulocyte count

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2
Q

What conditions lead to an elevated INDIRECT bilirubin?

A

Hemolysis

Gilbert’s syndrome

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3
Q

What are causes of microcytic anemia?

A

Sideroblastic
Thalassemia
Iron Deficiency
Chronic Disease

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4
Q

What is the most common cause of sideroblastic anemia with basophilic stippling?

A

Lead

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5
Q

What problems do patients with one alpha globin chain (Hgb H) have?

A

stillbirth (hydrops fetalis)

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6
Q

Another name for beta-thalassemia major?

A

Cooley anemia

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7
Q

What do people with Hgb H disease need?

A

Folic acid

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8
Q

Most common form of anemia?

A

Iron deficiency

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9
Q

What is the hallmark of iron deficiency?

A

Pica

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10
Q

What are the most common causes of a macrocytic anemia?

A

B12 and folate deficiency

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11
Q

Cell findings pathognomonic for folate deficiency?

A

macro-ovalocytes
hypersegmented PMN cells
Howell-Jolly bodies

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12
Q

Most common cause of folate deficiency?

A

diet

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13
Q

Most common cause of pernicious anemia?

A

Lack of Intrinsic Factor

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14
Q

What test looks for antibodies on RBC thus looking for hemolytic anemia?

A

Coombs

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15
Q

What stain looks for G6PD?

A

Heinz body

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16
Q

What daily / lifelong medication should be considered for all patients with sickle cell disease?

A

Hydroxyurea

17
Q

What do atypical lymphocytes point towards?

A

EBV (mono)

18
Q

What do Auer Rods point towards?

A

AML

19
Q

What cells are pathognomonic for CLL?

A

smudge cells

20
Q

Which cells point towards Hodgkin’s Disease?

A

Reed-Sternberg

21
Q

What virus is seen in 50% of Hodgkin’s?

A

EBV

22
Q

What is a trigger for lymph node pain in Hodgkins?

A

pain after alcohol

23
Q

Where is the pathology in multiple myeloma?

A

plasma cells

24
Q

Most common complaint of patients with multiple myeloma?

A

Bone pain (lower back pain)
infections
anemia

25
Q

Hallmark of multiple myeloma?

A

monoclonal spikes on serum electrophoresis

bence-jones proteins

26
Q

Most common congenital coagulopathy?

A

von Willebrand disease

27
Q

What is Christmas disease?

A

Hemophilia B (Factor IX deficiency)

PANRE (18 decks)

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