Hematological Assessment Flashcards
What is the most common nutrient deficiency in the word?
Iron intake leads to anemia
What nutrient deficiencies cause anemia?
Iron, Vitamin B-12, Folate
Anemia
Deficiency in the oxygen carrying capacity of blood due to decreased erythrocyte mass; too few RBCs or not enough hemoglobin; often a co-morbidity.
Cellular basis of anemia
Erythrocyte loss (bleeding); increased erthyrocyte production (hemolysis); or Decreased erythrocyte production (low erythropoietin, decreased marrow response to erythropoietin).
Two main hormones involved in anemia
EPO (erythropoietin) and Hepcidin
EPO
Erythropoietin; secreted by the kidneys, increases the rate of productions of RBCs in response to falling levels of oxygen in tissues
Hepcidin
Produced by the liver; Prevents iron overload in the body; inhibits intestinal reabsorption, iron recycling, and iron mobilization from hepatic stores.
EPO and Hepcidin levels and anemia
EPO lower = increased risk of anemia; Hepcidin Rise = increased risk for anemia.