heart Flashcards
what drug class is Warfarin in
Vit K antagonists
how long does warfarin take to work
takes 2-5 days to work
ALSO long lasting
what is the action of warfarin
works in liver to block Vit K synthesis of dependent clotting factors 2,7,9,10
what is the side effect of Warfarin
hemorrhage (especially hepatic ally impaired pt)
N/V, alopecia, urticaria, dizziness, muscle and joint pain
What is the black box warning of Warfarin
Fatal bleeding
what do we monitor when administering Warfarin
INR (2-3 or 2.5-3.5 for prosthetic heart valve)
What is a patient teaching with Warfarin
tell pt to stay consistent with potassium intake
do not decrease or increase
why do we give Heparin
DVT,PE, MI, stroke, gynocological surgeries, and bed rest for more than 5 days
What are the side effects of Heparin
hemorrhage, HIT (heparin induced thrombocytopenia)
what should the nurse monitor when administering Heparin
aPPT (46-70)
what is the antidote for Heparin
protamine sulfate
what drug class is Alteplase
Thrombolytics
what is the action of Alteplase
encourages plasminogen to plasmin which breaks down clot
Clot buster
what do we give Alteplase for?
MI, PE and ielofemoral thrombosis
what are the SE’s of Alteplase
hemorrhage and brain bleed
what are the contraindications for Alteplase
65+ yrs of age
risk of embolism in afib pts
who can administer alteplase
critical care nurses, continuous cardiac monitoring and ECG results
Why do we minimize IM injections when giving Alteplase
hematoma
What drug class is Lisinopril in?
Ace inhibitors
what is the action of Lisinopril
inhibits conversion of angiotensin 1 to 2
why do we give lisinopril
hypertension and heart failure