Diabetes Flashcards

1
Q

What drug class is metformin?

A

Biguanide

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2
Q

What is the action of metformin?

A

↓ production of glucose, decrease intestinal absorption, ↑ insulin sensitivity

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3
Q

Why do we give metformin

A

Type Il diabetes, antihyperglycemic
Helps promote weight loss

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4
Q

What are the side effects of metformin

A

Lactic acidosis, dizzy, cramps, n/v/d

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5
Q

What is the black box warning of metformin

A

Lactic acidosis over 80yrs old

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6
Q

What do he assess for when administering Metformin

A

Ast/alt
Bun/Cr
Muscle cramps

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7
Q

Why is metformin an ideal drug for hyperglycemia

A

No hypoglycemia effects

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8
Q

When do we give metformin?

A

With meals

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9
Q

What drug class is exenatide in?

A

Glucagon like peptide 1 receptor agonist (GLP-1)

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10
Q

What is the action of Exenatide?

A

↑ blood glucose by stimulating liver to convert glycogen to glucose, opposes insulin

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11
Q

Why do we give exenatide

A

Treat hypoglycemic effects

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12
Q

What are the contraindications of exenatide?

A

Depleted glycogen stores (starvation, adrenal insufficiency or chronic hypoglycemia)

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13
Q

Insulin
What increases effects?

A

Increases: ace, ETOH, antibiotics and beta blockers

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14
Q

Insulin
What decreases effects?

A

Adrenergic, steroids, estrogen, levothyroxine

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15
Q

What wind of insulin is human r

A

Regular

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16
Q

What does humalin R look like

A

Clear

17
Q

What is the onset of Human R

A

30 min - 1hr

18
Q

When does Human R peak

A

2-3 hrs

19
Q

What is the duration of Humalin R

A

5-7 hrs

20
Q

What wind of insulin is Human N

A

Intermediate

21
Q

What does Humalin N look like

A

Cloudy

22
Q

How do we give Humalin N

A

Only sub Q

23
Q

What is the onset of Humalin N

A

1-1.5hrs

24
Q

What is the peak of humalin N?

A

8-12 hrs

25
Q

What is the duration of humalin N?

A

18-24 hrs

26
Q

What kind Of insulin is glargine?

A

Long acting, basal insulin

27
Q

When do we give glargine?

A

Bedtime

28
Q

What is the onset of glargine?

A

1hr

29
Q

What is the peak of glargine?

A

None

30
Q

What is the duration of glargine?

A

24 hrs