Gut Training Flashcards

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1
Q

A high carbohydrate diet will increase the density and activity of what transporter

This increase results in what

A

Sodium dependent glucose transporter 1

Greater carbohydrate absorption and oxidation

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2
Q

Does the mechanism of action differ for upper and lower GI problems

A

Yes

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3
Q

Saturation of ________ transporter will prevent increases in glucose absorption

A

SGLT1

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4
Q

The rate limiting factor of carbohydrate oxidation (skeletal muscle) is the ______________ ___________ __ _____________

A

Intestinal absorption of carbohydrate

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5
Q

Symptoms of GI issues are more likely to be exacerbated in what two conditions

A

Hot weather

Dehydration

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6
Q

What 2 non-nutritive sweeteners increase SGLT1 expression

A

Acesulfame K

Saccharin

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7
Q

What luminal transporter assists glucose OR fructose

A

Glucose: SGLT1

Fructose: GLUT5

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8
Q

T/F
A high carbohydrate diet can increase SGLT1 protein and transport capacity for glucose

A

True

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9
Q

Why would a hydrogen breath test be used

A

Measure carbohydrate absorption

High: malabsorption
Low: good absorption

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10
Q

What organs are the main targets of gut training

A

Stomach

Intestine

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11
Q

Which organ, stomach or intestine, has faster adaptations without training

A

Stomach

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12
Q

How many different tests are used to populate the gut training score

A

5

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13
Q

What mechanism is fructose ingestion associated with in regards to negative gut issues

A

Associated with increased small intestinal water content resulting in GI symptom induction

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14
Q

Causes exercise induced gastrointestinal syndrome

A

Splanchnic hypoperfusion

Intestinal epithelial injury

Increased intestinal permeability

Systemic responses (endotoxaemia, cytokinaemia)

Impaired intestinal nutrient absorption

Stress induced increases in sympathetic drive and reductions in enteric nervous system activity which alters intestinal motility and absorption capacity

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15
Q

What marker is used to assess intestinal injury

A

Intestinal Fatty Acid Binding Protein (I-FABP)

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16
Q

Repeated ingestion of carbohydrates has been shown to maintain a consistent intragastric pressure resulting in…

A

Enhanced gastric emptying rate and improved stomach comfort

17
Q

What is a more practical and less invasive method for estimating upper limit for carbohydrate intake tolerance

A

Measuring total carbohydrate oxidation using indirect calorimetry at the point of stressed muscle glycogen stores while consuming a multi-transportable carbohydrate formulation during exercise