Gross Pathology of Respiratory System Flashcards
Alpaca congenital malformation
Choanal atresia
Four lesions associated with Brachycephalic Airway Obstruction Syndrome
- stenotic nares
- elongated soft palate
- tracheal hypoplasia
- everted laryngeal sacccules
Species affected by tracheal collapse
(chondromalacia)
Dogs, horses (ponies and American minis)
Common horse laryngeal malformation; contributes to what other condition?
Epiglottal hypoplasia; Dorsal Displacement of the Soft Palate
Possible causes of hypoplastic lungs
Anything that prevents inflation:
* Hydrops fatalis/hydramnios (fluid in amnion)
* Dexter bulldog calves with anasarca
* Congenital diaphragmatic hernia
* Intrathoracic mass
Cause of atelectatic lungs in foal
Equine neonatal respiratory distress syndrome- reduced production of surfactant proteins
Will see expiratory grunt or bark at birth, hypoxemia, heart failure
Flat pigmented areas of lung; only acquired version of this disease
melanosis; Nero cecilian pigs eating acorns with phenols
Ddx for erosive lesion on nose of white cat
- squamous cell carcinoma
- Cryptococcus infection
- Sporotrichosis infection
Infiltrative tumor from sinus of horse; origin?
Squamous cell carcinoma; epithelium around tooth
Which types of carcinomas arise from where within the nasal cavity?
- Rostral- SCC
- Middle- transitional nasal carcinoma
- Caudal- adenocarcinoma (b/c glandular)
Nasal tumor in sheep; cause?
Nasal adenocarcinoma; beta retrovirus- Enzootic Nasal Tumor virus 1
What type of lymphoma do cats get in the nasal cavity?
B cell
What type of nasal tumors do dolicocephalic breeds get?
chondrosarcoma
Laryngeal tumor in dog; distinguishing histologic feature
rhabdomyoma/sarcoma; big pink cells with bright pink granules (mitochondria)
Pulmonary adenocarcinoma growth pattern
Lepidic (along alveolar septa)
Horse airway or lung tumor is most likely…
Granular Cell Tumor
from Schwann cells
Metastasizes to lungs in rabbits
Primary uterine carcinoma
Tumors that metastasize to lungs (3); source
- hemangiosarcoma; right atrium
- melanoma; anywhere
- carcinoma; mammary
Causes “driving sickness” in sheep 4-6 years of age
Endogenous beta retrovirus (jaagsiekte) causing pulmonary adenocarcinoma
Where does mesothelioma occur in the dog? rats? NHPs?
Dog- pleura and pericardium
Rats- abdomen
NHPs- diaphragm
Ddx for mesothelioma in white-tailed deer?
Mycobacterium bovis
Top two viral ddx in cat URI; secondary bacterial infections?
Feline herpesvirus
Feline calicivirus (RNA virus)
; Chlamydia felis, mycoplasma felis, mycoplasma gati
Where does herpesvirus go latent in the cat?
Trigeminal ganglion
Optic nerve
Cornea
Distinguishing feature of alpha herpes virus
Necrosis in airways