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Gross Pathology > Gross pathology hemolymph > Flashcards

Gross pathology hemolymph Flashcards

1
Q

What causes an enlarged tonsil with hyperplastic change and centrally dilated lymphatics

A

Lymphangiomatous tonsillar polyp

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2
Q

Tonsils with hemorrhage and necrosis in chickens

A

Newcastle disease (avian paramyxovirus type 1)

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3
Q

What causes hemorrhage in the thymus?

A

Bromethalin (rodentacides), trauma, snake venom

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4
Q

What causes thymic atrophy with dark fluid filled cysts in primates?

A

Viral or steroid induced cystic atrophy

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5
Q

What causes small lymphoid organs w. hemorrhage/necrosis?

A

Virus (CSF)

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6
Q

Paraneoplastic syndromes with thymoma

A

Exfoliative dermatitis
Paraneoplastic exophthalmos
Myasthenia gravis

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7
Q

Which lymphoma is FeLV driven?

A

Thymic lymphoma

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8
Q

Two presentations of lymphoma in ferrets

A

Young- visceral B cell
Older- large lymph nodes only, T cell

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9
Q

Which mice get thymic lymphoma?

A

AKR (almost 100%), C57 and C58

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10
Q

What cow breed gets congenital lymphedema?

A

Escher

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11
Q

What causes congenital lymphedema

A

Podoplanin deficiency

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12
Q

Cause of tiny, nonexistent LNs

A

SCID

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13
Q

Cause of lymphoid necrosis in bursa (will be small)

A

Avian birnavirus (Infectious Bursal Disease); attacks B cells

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14
Q

Cause of large bursa with edema; other gross lesion

A

Avian circovirus (Chicken Anemia Agent); attacks T cells, so also thymus atrophy

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15
Q

Cause of enlarged LNs in a macaque

A

early SIV (lentivirus; loves lymphocytes)

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16
Q

Cause of enlarged LNs in a pig

A

Porcine circovirus type 2

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17
Q

Cause of enlarged LN in a dog

A

Dimorphic fungi- histoplasma, blastomyces
Coccidioidomycosis

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18
Q

Cause of enlarged LN in cattle

A

Hairy vetch toxicity (vicia villosa)

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19
Q

What kind of lymphoma is in cat GI?

A

T cell

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20
Q

What kind of lymphoma is in the dog nose?

A

B cell

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21
Q

What antigen is expressed on FeLV infected cells?

A

Feline oncovirus-associated cell membrane antigen (FOCMA)

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22
Q

What type of lymphoma is caused by BLV

A

B cell

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23
Q

Organs affected by BLV

A

Abomasum>heart>spinal cord>kidney>uterus

24
Q

What kind of lymphoma is most common the dog?

A

Diffuse large B cell

25
Q

What kind of lymphoma is only in 1 node, and is less aggressive?

A

T zone lymphoma

26
Q

What type of lymphoma is most common in the horse?

A

Alimentary T cell rich B cell lymphoma

27
Q

What is the cause of lymphoma in the mouse? What type?

A

Murine leukemia virus
B cell from spleen

28
Q

Which rat strain gets lymphoma? What kind?

A

Fischer 344; large granular cell leukemia

29
Q

What causes lymphoma in guinea pigs?

A

Cavian leukemia

30
Q

What is the cause of lymphoma in hamsters?

A

Polyoma virus! not a retrovirus

31
Q

How do hamsters get polyoma virus?

A

transmitted through urine

32
Q

Where do rabbits get lymphoma?

A

kidneys

33
Q

Cause of lymphoma in baboons

A

Herpesvirus papio 1 (this is weird because 2 is usually the neoplasm causing one)

34
Q

Cause of lymphoma in new world monkeys

A

Herpes virus saimiri type 2 (this is how it usually is, 2 for tumor)

35
Q

Cause of lymphoma in macaques

A

SIV or lymphocrytpovirus (if immunosuppressed)

36
Q

What gross lesions are seen with Marek’s disease (avian herpesvirus type 2)?

A

T cell follicular lymphoma (classic)
Lymphocytic perineuritis of sciatic nerve (splay leg)
Gray eye

37
Q

How to differentiate lymphoid leukosis from Marek’s?

A

Viscera, bursa in an older bird- leukosis
B cell or T cell

38
Q

Characteristic gross lesion with leukosis virus

A

Nakanuke feathering

39
Q

Foal with enlarged spleen and icterus, followed by hematomas and infarcts

A

Neonatal isoerythrolysis

40
Q

Tumor that older cats get in the spleen

A

Visceral mast cell tumor

41
Q

What tumor do cheetah’s get in the spleen?

A

Myelolipoma

42
Q

Lentivirus effect on spleen

A

Initially, lymphoid hyperplasia, then lymphoid atrophy

43
Q

Cause of lymphoid hyperplasia in horse spleen

A

Equine Infectious Anemia

44
Q

Cause of lymphoid hyperplasia in a cat

A

FIV

45
Q

Macaque with spleen white pulp outlined by hemorrhage

A

Simian hemorrhagic fever (arterivirus)

46
Q

Cause of splenomegaly with hemorrhage and histiocytosis in pheasants, poultry

A

Marble Spleen Disease (Turkey adenovirus 3)

47
Q

Cat with fibrin on spleen

A

FIP

48
Q

Miliary (embolic) abscesses in the spleen of a cat

A

Francisella tularensis

49
Q

Difference between anaplasma marginale and babesia

A

Babesia is extravascular hemolysis, much worse clinically

50
Q

Icteric cat

A

Mycoplasma haemofelis

51
Q

Cause of bone marrow erythroid hyperplasia (dark red marrow) in horses

A

EIA (lentivirus)

52
Q

Three causes of bone marrow loss

A

Neoplasia
Viral
Nutritional deficiency

53
Q

Bone marrow appearance with chicken anemia virus (circovirus)

A

No erythroid precursors- pale bone marrow

54
Q

What causes nutritional marrow loss in chickens?

A

Folate deficiency

55
Q

Bone abscess in chickens cause

A

Enterococcus cecorum (sepsis)

56
Q

Signs seen with multiple myeloma

A

Boney resorption due to osteoclast activation
Monoclonal gammopathy
Bence Jones proteins in urine
Hypercalcemia (from osteoclasts)
Cytoplenias due to replacement

Gross Pathology (23 decks)

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