Gross path of lab animals

Question 1

Two pinworm species in mice and rats

Answer 1

Syphacia obvelata
Aspicularis tetraptera

Question 2

Cause of proliferative enteritis

Answer 2

Citrobacter rodentium

Question 3

Cause of adynamic ileus or megacolon

Answer 3

Clostridium piliforme

Question 4

Three causes of diarrhea in mouse pups

Answer 4

Rotavirus
C piliforme
Mouse enterotropic coronavirus

Question 5

Cause of bronchopneumonia (3)

Answer 5

Mycoplasma pulmonis
Pasteurella pneumotropica
Corynebacterium kutscheri

Question 6

Cause of interstitial pneumonia (3)

Answer 6

Acidophilic macrophage pneumonia
Pneumocystis murina
Sendai virus

Question 7

Cause of liver necrosis in mouse

Answer 7

Mouse polytropic coronavirus

Question 8

Tapeworm in abdominal cavity of rats- larval and adult name; associated lesion

Answer 8

Cysticercus fasciolaris
Taenia taeniaformis

Hepatic sarcomas

Question 9

Mouse strain that gets ovarian teratomas

Answer 9

LT/Sv

Question 10

Mouse strain that gets testicular teratomas

Answer 10

129

Question 11

If liver and uterine tumor, it’s a

Answer 11

Histiocytic sarcoma

Question 12

Morph for polyarteritis nodosa in rats; unaffected organ

Answer 12

Proliferative and necrotizing mesenteric arteritis; lungs

Question 13

What tumors are Fischer 344 rats predisposed to?

Answer 13

LGL leukemia
Mesothelioma
Testicular tumors

Question 14

What is the only lesion that occurs under the ear of a rat?

Answer 14

Zymbal’s gland tumor

Question 15

Cause of ulcerative orogenital lesions and liver necrosis in macaques

Answer 15

Macacine herpesvirus 1

Question 16

Cause of ulcerative oral lesions and liver necrosis in NWPs

Answer 16

Saimirine herpesvirus 1

Question 17

Cause of proliferative oral lesion in baboons

Answer 17

Herpesvirus papio type 2

Question 18

Cause of pseudotumors in gut; also causes necrotic hemorrhagic lesions

Answer 18

Macacine herpesvirus 3 (cytomegalovirus)

Question 19

Cause of lymphoproliferative disease in all NHPs

Answer 19

Gammaherpesvirus

Question 20

What combination of viruses do macaques need to get lymphoma?

Answer 20

SIV or simian retrovirus
plus macacine gammaherpesvirus 4

Question 21

What is the classic oral lesion associated with simian retrovirus 2

Answer 21

Noma- necrotizing mandibular osteomyelitis

Question 22

Oral co-infection associated with simian retrovirus 2

Answer 22

Shigella flexneri- necrotizing gingivitis

Question 23

Triad associated with francisella tularensis

Answer 23

Ileal necrosis, mesenteric lymph node necrosis, splenic necrosis

Question 24

Cause of malaria in primates; lesions?

Answer 24

Plasmodium coatni; enlarged, dark brown liver, anemia

Question 25

Cause of gastric mucosal hyperplasia with red worm

Answer 25

Nochtia nochti

Question 26

Greenish purplish fibrinonecrotic colon

Answer 26

Shigella flexneri

Question 27

Differentials for edematous, proliferative gut

Answer 27

Amyloid Mycobacterium Campylobacter