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Gross Pathology > Gross Pathology of Respiratory System 2 > Flashcards

Gross Pathology of Respiratory System 2 Flashcards

1
Q

What type of lymphoma occurs in the nasal cavity of cats?

A

B cell lymphoma

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2
Q

Granular Cell Tumor features

A

Horse lung, dog larynx, rat brain, diastase resistant (granules are mitochondria, not glycogen)

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3
Q

What do A strain mice get?

A

Tumors in general due to activation of K-RAS oncogene, specifically pulmonary adenocarcinoma

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4
Q

Hemangiosarcoma locations in dog

A
  1. Right atrium
    Lung, liver, spleen
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5
Q

Bloody nose syndrome in macaques is caused by

A

Moraxella macacae

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6
Q

Three causes of Glasser’s disease (polyserositis)

A

Glaesserella parasuis
Streptococcus suis
Mycoplasma hyorhinis

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7
Q

Causes of nasal abscesses in cattle

A

Trueperella pyogenes
Fusobacterium necrophorum

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8
Q

Causative agent of Strangles; most likely location

A

Streptococcus equi sub. equi; submandibular LN, bastard strangles if not head/neck

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9
Q

What causes progressive atrophic rhinitis in pigs? nonprogressive?

Typical age range?

A

Progressive:
Pasteurella multocida type D toxin (dermonecrotizing toxin)
Bordetella bronchiseptica

Nonprogressive:
Bordetella

Age: 8-12 weeks

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10
Q

What causes atrophic rhinitis in rabbits?

A

Bordetella bronchiseptica
Pasteurella multocida?

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11
Q

Agent and name for necrotic rhinitis in swine

A

Fusobacterium necrophorum; Bullnose

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12
Q

Cause of chronic proliferative rhinitis in sheep

A

Salmonella enterica subs. diarizonae

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13
Q

Causative agent of guttural pouch empyema/eustachitis

A

Strep equi sub equi, later colonized by strep equi sub zooepidemicus

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14
Q

Gross finding with infectious coryza?

A

infraorbital sinus distension, facial edema, URI

Avibacterium paragallinarum

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15
Q

Causative agent of Infectious Coryza in poultry

A

Avibacterium paragallinarum

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16
Q

Turkeys with soft swollen head have…

A

Avian pneumovirus

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17
Q

Poultry with hard swellings of the infraorbital sinuses have…

A

Mycoplasma gallisepticum; infectious sinusitis

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18
Q

Sparrows and birds with infectious sinusitis or chronic respiratory disease

A

Mycoplasma gallisepticum

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19
Q

What causes turkey coryza? unique feature of this bacteria?

A

Bordetella avium; infectious sinusitis, blepharitis, conjunctivitis, submandibular edema; lysis of tracheal rings (chondromalacia) due to cytotoxin

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20
Q

Causes soap bubble lesions in air sacs and sinuses of turkeys

A

Mycoplasma meleagridis

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21
Q

Causes suppurative air sacculitis in NHPs (2)

A

Klebsiella pneumoniae
Streptococcus pneumoniae

22
Q

Causes necrotic laryngitis in young cattle (aka calf diphtheria) (2)

A

Fusobacterium necrophorum
Histophilus somni

23
Q

Gram negative bacteria

A

Bordetella bronchiseptica
Escherichia coli
Klebsiella pneumoniae
Pasteurella multocida
Francisella tularensis
Mannheimia hemolytica

24
Q

Gram positive bacteria

A

Staph
Strep

25
Q

What agent causes severe bronchopneumonia with hemorrage and necrosis in guinea pigs?

A

Bordetella bronchiseptica

26
Q

Bordetella bronchiseptica virulence factors

A

RTX toxin
Dermonecrotic toxin
Adherence factors (hemagglutinin)
Fimbriae

27
Q

Agent that causes big ugly hemorrhagic leaky lungs in the dog

A

Extra intestinal pathogenic E.coli (ExPEC)
Streptococcus canis
Streptococcus equi subs. zooepidemicus
Salmonella

Not bordetella, would be collapsed

28
Q

E.coli virulence factors

A

Cytotoxic necrotizing factor 1
Fimbriae
Hemolysins
Adhesins

29
Q

Francisella tularensis causes what gross lesions in the cat?

A

Splenic necrosis
Peyer’s patch and mesenteric LN necrosis
Embolic pneumonia (multifocal to coalescing suppurative embolic pneumonia)

30
Q

Diffuse, chronic, proliferative, suppurative pyothorax (ragu) in cat or dog chest

A

Actinomyces (will see sulfur granules)
Nocardia asteroides- no sulfur granules, weakly acid fast

31
Q

What causes “snuffles” in rabbits? Ddx?

A

Pasteurella multocida; staphylococcus aureus

32
Q

Gross findings with staphylococcus aureus in rabbits

A

Creamy white exudate, necrotic lymph nodes, abscesses in lungs and viscera

33
Q

Shipping fever of NHPs

A

Klebsiella pneumoniae

34
Q

Fibrin in cavities of a NHP (Fibrinosuppurative meningitis, bronchopneumonia, etc.)

A

Streptococcus pneumoniae

35
Q

Lung abscess in a mouse- differentials?

A

Pasteurella pneumotropica, streptobacillus moniliformis, staph, corynebacterium kutscheri

36
Q

Morphologic diagnosis for mycoplasma pulmonis in mice and rats? Virulence factors?

A

Suppurative bronchopneumonia with bronchiectasis
Superantigen- BALT hyperplasia

37
Q

How to differentiate mycoplasma pulmonis and corynebacterium kutscheri grossly in mouse or rat?

A

Corynebacterium will affect all lungs, because hematogenous

38
Q

How to differentiate mycoplasma pulmonis and filobacterium rodentium grossly in mouse or rat?

A

Can’t grossly, same lesions. On histo, will see filamentous bacteria with filobacterium

39
Q

Morphologic diagnosis for rhodococcus equi in 1-6 month foal?

A

Multifocal to coalescing granulomatous pneumonia

40
Q

Six agents involved in Shipping Fever in cattle

A
  1. Pasteurella multocida
  2. Bibersteinia trehalosi
  3. Mannheima hemolytica (classic)
  4. Histophilus somni
  5. Mycoplasma mycoides SCT
  6. Mycoplasma bovis
41
Q

Virulence factors associated with mannheimia hemolytica

A

Endotoxin
Polysaccharide capsule
RTX toxin- oat cells leukocytotoxic

42
Q

Gross lesions associated with Shipping Fever in cattle

A

Cranioventral suppurative bronchopneumonia with bronchiectasis and fibrinous pleuritis

43
Q

How does mycoplasma mycoides subsp. mycoides look different than shipping fever?

A

Unilateral

44
Q

What causes caseous lymphadenitis in small ruminants?

A

Corynebacterium pseudotuberculosis

45
Q

What causes enzootic pneumonia in grower/finisher pigs?

A

Mycoplasma hyopneumoniae

46
Q

Three causes of fibrinous polyserositis in pigs?

A

Streptococcus suis
Glaesserella parasuis
Mycoplasma hyorhinis

47
Q

Worst pneumonia in pigs

A

Actinobacillus pleuropneumoniae

48
Q

Pig pneumonia that can become sepsis

A

Actinobacillus suis

49
Q

Agents that cause pneumonia and sepsis in poultry

A

Pasteurella multocida
Ornithobacterium rhinotracheale

50
Q

Causes soap bubble exudate within mesentery of turkeys

A

Mycoplasma meleagridis

Gross Pathology (21 decks)

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