Gross pathology of cattle- liver Flashcards

1
Q

Cause of fibrinopurulent omphalophlebitis

A

Always related to colostrum deficiency
Navel ill- local infection
Joint ill- systemic, liver abscesses

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2
Q

Other name for Foothill Abortion

A

Epizootic Bovine Abortion

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3
Q

Causative agent of Epizootic Bovine Abortion (EBA)

A

Pajaroellobacter abortibovis

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4
Q

Gross lesions with Epizootic Bovine Abortion (EBA)

A

Aborted fetus with:
Cobblestone liver (granulomatous hepatitis)
Granulomatous splenitis
Granulomatous thymitis (nothing else causes this)

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5
Q

Cause of centrilobular necrosis in young ruminants (worse in sheep)

A

Rift Valley Fever (bunyavirus)

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6
Q

Gross lesions with Rift Valley Fever

A

Hemorrhage (small petechiae to severe GI bleeds)
Characteristic hepatocellular centrilobular necrosis
Abortion

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7
Q

Cause of multifocal to coalescing white dots of variable sizes (necrotizing or suppurative hepatitis)

A

Gram negative sepsis
-In very young, coliforms and umbilical infection
-In older animals, Salmonella dublin

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8
Q

What gross lesion does Salmonella dublin cause (other than sepsis, hepatitis, or GI issues)

A

Fibrinonecrotic cholecystitis

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9
Q

Cause of infarcts in liver (well-demarcated areas of necrosis)

A

Fusobacterium necrophorum- flat, blanched, well-demarcated, secondary to ruminal acidosis

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10
Q

Cause of yellow granular granulomas in liver

A

Mycobacterium bovis

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11
Q

Three main liver flukes

A

Fasciola hepatica- lives in bile ducts, results in Clostridium hemolyticum and redwater (bacillary hemoglobinuria)
Dicrocoelium dendriticum- within bile ducts, causes veryyyy prominent BDs
Fascioloides magna- too big to live in bile ducts, within liver

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12
Q

Gross lesion of clostridium hemolyticum (other than hemoglobinuria)

A

Ischemia, infarcts in liver

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13
Q

Other bacterial infection secondary to liver flukes

A

Clostridium novyi (Black Disease)

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14
Q

Gross lesion caused by clostridium novyi

A

Multiple hepatic infarcts

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15
Q

Cause of hydatid cyst in liver

A

Echinococcus granulosus

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16
Q

What causes nutmeg liver (entire pathogenesis)

A

Hypoxia secondary to chronic passive congestion (altitude disease, heart disease, etc.) –> centrilobular hepatocyte necrosis –> fibrosis between central veins

17
Q

Gross appearance with hepatic toxins

A

Centrilobular necrosis with replacement with hemorrhage
ex. sawfly ingestion

18
Q

Toxin that causes shrunken fibrotic liver

A

Sporidesmin toxicity from Pithomyces chartarum (fungus)

19
Q

What toxin causes a shrunken floppy dish rag liver?

A

Lantana toxicity

20
Q

What causes a small, putty colored liver

A

Copper toxicity

21
Q
A