GoosPasture syndrome Flashcards by Manu Hatsa | Brainscape

Q

Goodpasture syndrome: cause

A

anti-GBM antibody disease -> damage to the basement membrane in lungs + kidneys

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Q

Goodpasture syndrome: S, C

A

cough, hemoptysis, dyspnea
Hematuria, proteinuria

Complication: chronic renal failure

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Q

Goodpasture syndrome: D

A

Light microscopy: Crescentic glomerulonephritis
Electron microscopy: Diffuse thickening of glomerular basement membrane
Immunofluorescence: Linear deposition along basement membrane

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Q

Goodpasture syndrome: T

A

Prednisone
cyclophosphamide,
plasmapheresis to filter plasma/fluid of blood (reduces risk of chronic renal failure

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