Chronic tubulointerstitial nephritis

Question 1

Chronic tubulointerstitial nephritis: diagnosis

Answer 1

• Imaging test will show small kidneys + evidence of scarring and asymmetry
• Renal biopsy used mainly for showing the progression of the tubulointerstitial disease

Question 2

Chronic tubulointerstitial nephritis: anatomical changes

Answer 2

• glomeruli vary from normal to completely destroyed
• tubules are absent or atrophied
• tubular lamina may show dilation
• interstitium contains inflammatory cells and fibrosis