Chronic pyelonephritis Flashcards

1
Q

Chronic pyelonephritis: causes

A
  • Repeated episodes of acute pyelonephritis -> Leads to fibrosis, renal interstitium scarring, renal tubules atrophy
  • Vesicoureteral reflux (VUR) -> can be due to Failure of vesicourethral orifice -> urine moves backward up urinary tract from bladder. May result from primary congenital defect, bladder outlet obstruction
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2
Q

Chronic pyelonephritis: RF

A
  • Urinary tract abnormalities
  • catheter
  • diabetes
  • immunocompromised status
  • BPH
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3
Q

Chronic pyelonephritis: S

A
  • May be asymptomatic
  • Hematuria, polyuria/nocturia
  • Flank pain
  • Inflammatory response
  • Leukocytosis; fever; chills; nausea, vomiting; gerontologic (e.g. altered mental status)
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4
Q

Chronic pyelonephritis: D

A
  • Urine culture, bacteria
  • Pyuria
  • hematuria
  • bacteriuria
  • leukocyte casts
  • Medical imaging -> will show small kidneys
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5
Q

Chronic pyelonephritis: T

A

Medication:
- antibiotics

Surgery:

  • Correct kidney obstruction/VUR
  • Nephrectomy: removal of part/all of damaged kidneys
  • Kidney transplant
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