GM - Anaerobes

Question 1

Gm - anaerobes facts (4)

Answer 1

treat with oxygen, surgical drainage, removal of necrotic tissue, macrolide, penicillins, etc.
-not ahminoglycosides

-culture on rich media with either kanamycin or vance or bile

usually infection has mixture of aerobes and anaerobes-aerobes make environment better for anaerobes

spread from endogenous sources

• dominates LI, mouth
• small in SI, distal urethra, vag

Question 2

Gram negative anaerobes to know

Answer 2

Bactericides fragilis
Prophyrmonas/prevotella
Fusobacterium
Veillonella

Question 3

Bactericides fragilis

• shape
• habitiat
• disease
• virulence

Answer 3

-rods
-large intestine
-abdoinal infections/abcesses, septicemia, diarrhea
LPS has no lipid A and low virulence, secretes exotoxin that cleaves E-cadherin to loosen enterocyte junctions, has high inflammatory capsule (also anti-phagocytic)

Question 4

Prophyrmonas/prevotella

• shape
• habitiat
• disease
• virulence

Answer 4

• rods
• oral
• infections of head/neck/respitory tract/bite wounds
• porphyromonas make black pigment and colonies fluoresce red under UV, endotoxic LPS

Question 5

Fusobacterium

• shape
• habitiat
• disease
• virulence

Answer 5

• rods
• oral
• absecceses/otitis media
• endotoxic LPS

Question 6

Veillonella

• shape
• habitiat
• disease
• virulence

Answer 6

-cocci
-oral flora
n/a
-endotoxic LPS