Antibiotic Resistance Flashcards
1
Q
Vancomycin
A
inserts lactic acid in place of terminal D-ALA
common in ternococcus
2
Q
Amino glycoside
- (kill or inhibit growth?)
- mech
A
bactericidal
from plasma encoded enzymes that modify amino sugars that are added to OH or amino groups-so can’t bind to 30S ribosome
some resistances have been beaten by moleoal of OH groups or addition of kargebulky groups
3
Q
Macrolide and Streptogrammins
A
bactericidal
adds emthl group to base of RNA in 50S submit
-transposon ermA gene
4
Q
Tetracycline
A
bacteriostatic
tetracycline-encoded transport protein pumps out of cell