Antibiotic Resistance Flashcards

1
Q

Vancomycin

A

inserts lactic acid in place of terminal D-ALA

common in ternococcus

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2
Q

Amino glycoside

  • (kill or inhibit growth?)
  • mech
A

bactericidal

from plasma encoded enzymes that modify amino sugars that are added to OH or amino groups-so can’t bind to 30S ribosome

some resistances have been beaten by moleoal of OH groups or addition of kargebulky groups

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3
Q

Macrolide and Streptogrammins

A

bactericidal

adds emthl group to base of RNA in 50S submit
-transposon ermA gene

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4
Q

Tetracycline

A

bacteriostatic

tetracycline-encoded transport protein pumps out of cell

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