GLYCERYL TRINITRATE Flashcards
1
Q
Action and side effects
A
Glyceryl trinitrate (GTN) is a potent vasodilator that
decreases preload by increasing venous capacity,
pooling venous blood in the peripheral veins, reducing
ventricular filling pressure and decreasing arterial
blood pressure (after load). Because of this cascade
it also causes vasodilation in the coronary arteries
that are in spasm and may assist the redistribution
of blood flow along the collateral channels in the
heart.
side effects: • Headache • Flushing • Hypotension • Syncope • Reflex tachycardia • Dizziness
2
Q
Indications, Contraindications, precautions
A
Suspected myocardialtype chest pain and Acute
Coronary Syndrome (ACS)
• Acute cardiogenic
pulmonary oedema
KSAR • Heart Rate <50 OR >150 beats per minute • Systolic BP <100mmHg • Acute CVA • Head trauma • Use of Viagra, Cialis or Levitra in previous 24 hours
Suspected inferior MI • Use of Viagra in previous 4 days • Intoxication • Cerebral Vascular Disease
3
Q
Dosages
A
adult: EMT 1 EMT 2 SUBLING 400mcg May be repeated every 5 min if required No max dose