Glucocorticoids

Question 1

The following is true of hydrocortisone

A. It is a long-acting agent

B. It is preferred steroid for anaphylaxis

C. It has very little anti-inflammatory activity

D. It is a fluorinated compound

Answer 1

B

Question 2

Glucocorticoids cause the following cellular changes that affect inflammation

A. Increased eosinophil count

B. Increased pathogen phagocytosis by macrophages

C. Decreased basophil count

Answer 2

C

Question 3

Among the following glucocorticoids, which has the highest potential for inducing

hyperglycemia or elevation of blood sugar?

A. Prednisone

B. Hydrocortisone

C. Triamcinolone

D. Dexamethasone

Answer 3

D

Question 4

The following practice decreases the likelihood of adverse effects with the use of

glucocorticoids

A. Give a higher dose at night than in the morning

B. For contact dermatitis, steroids should be administered systematically for faster effect

C. Use at the highest doses for optimal effect

D. Give prednisone rather than dexamethasone whenever possible

Answer 4

D

Question 5

The following are normal physiologic processes concerning steroid secretion which we

attempt to mimic whenever exogenous steroids are given

A. The peak of ACTH secretion is early in the morning at around 8 am

B. The peak of cortisol secretion is at 8 pm

C. Mineralocorticoid secretion peaks at 8 am

D. Cortisol secretion is lowest at around midnight

Answer 5

D

Question 6

The following is an expected metabolic effect of using glucocorticoids

A. Increased hepatic gluconeogenesis

B. Increased glycogen formation

C. Increased glycolysis by muscle

Answer 6

A

Question 7

The normal physiologic process

concerning steroid secretion which we

attempt to mimic when giving exogenous

steroids:

    A. Peak ACTH at 8 AM

    B. Peak cortisol levels at 8 PM

    C. Peak mineralocorticoid secretion at 

8 AM

    D. Cortisol levels are lowest at midnight

Answer 7

*