GI3 Histology: Liver, Spleen, Pancreas

Question 1

______ do not have linings!

Answer 1

bile canaliculi

Question 2

what is each arrow pointing at?

Answer 2

left: central vein
right: portal vein

Question 3

what kind of lobule is this?

Answer 3

a classic or anatomical liver lobule, with the arrows showing blood moving towards the center from portal triad to the central vein

Question 4

what kind of lobule is this?

Answer 4

a portal lobule, defining the movement of bile from central vein to portal triad

Question 5

what kind of lobule is this?

Answer 5

this is called a portal acinus, the areas are different zones of oxygen concentration. Zone 1 contains the cells on the periphery of the classical nodule and are receiving the most oxygen from the arterial blood supply, 2 is in the middle, and 3 has the lowest blood oxygen concentration.

Question 6

how do you tell between the bile duct and a hepatic artery on a slide?

Answer 6

the endothelial cells lining the hepatic artery will be sort of lumpy and not flat. this is an artifact but tells you these would normally be stretched out and muscular

Question 7

what are cholangiocytes for?

Answer 7

they are the epithelial cells that line the ducts and ductules

Question 8

what do Kupffer cells do? where are they located?

Answer 8

bilirubin production and degradation of RBCs

they are located in sinusoids in the capillaries

Question 9

what do hepatic stellate cells do? where are they located?

Answer 9

they are located in the space of Disse, they are antigen-presenting cells and contain lipid droplets in the cytoplasm

Question 10

what kind of cell is this and how do you know?

Answer 10

it is a ito cell or stellate liver cell because you can see the lipid droplets in the cytoplasm

Question 11

the bile ductule has a lining, which is made of ____cells, but the canaliculi does NOT have a lining

Answer 11

cholangiocyte

Question 12

what are the arrows pointing to?

Answer 12

bile canaliculi

Question 13

the gallbladder is a _______

Answer 13

muscular bag

Question 14

what is this?

Answer 14

the gallbladder

we know because the liver is pictured to the left, and on the right photo we can see columnar cells with muscle cells allowing contractions

Question 15

does the gallbladder have microvilli?

Answer 15

YES lol

Question 16

the pancreas has endocrine and exocrine functions/secretions. Name some for both

Answer 16

exocrine: mostly zymogens like trypsinogen, chymotrypsinogen, pancreatic lipase, and pancreatic amylase
endocrine: insulin, glucagon, somatostatin

Question 17

pancreatic acinar cells are involved in the ____ functions of the pancreas

Answer 17

exocrine, making zymogens

Question 18

label the pancreas diagram

Answer 18

from top going count clockwise:

tissue septum

ducts

exocrine cells in pancreatic acini

endocrine cells in pancreatic islet

Question 19

explain the two types of cells seen here

Answer 19

to the left are the acini of the pancreas involed in producing zymogens

to the right is an islet containing endocrine cells