Female Repro: Histology Flashcards
what are the 2 main cell types (and subtypes) in the ovary to look for on a slide?
oocyte, follicular cell (granulosa cells and theca cells)
what is the function of granulosa cells and theca cells in the ovary?
granulosa cells: make estrogen from androgens and secrete proteins
theca cells: secrete LH, secrete androgens for granulosa cells to convert into estrogen
the surface mesothelium of the ovary is called ______
germinal epithelium
label
A: cortex
B: medulla
C: corpus luteum, NOT the medulla
label
germinal epithelium (serosa)
tunica albuguinea
generally, all follicles contain a primary oocyte arrested in _______, and then it progresses into _____.The exception is in dogs where the ovulated egg is still in _____
meiosis 1, meiosis 2
meiosis 1
primordial follicles are lined with ______ cells
simple squamous follicular cells
what kind of follicle is this and why?
a primordial follicle because the cells are simple squamous
what kind of follicle is this and why?
a primary follicle because it is lined with simple cuboidal
what kind of follicle is this and why?
it is a secondary follicle because the cells are stratified cuboidal, and you can see the start of an antrum forming
what kind of follicle is this and why?
a tertiary follicle because the antrum is big and fully developed
Label
A: theca cells
B: Granulosa cells
C: antrum/follicular fluid
D: zona pellucida
E: basal lamina
F: cumulus oophorus (granulosa cells around the oocyte)
G: corona radiata (the cells immediately adjacent to the ZP)
theca cells make _____, and granulosa cells convert this into ____
androstenedione
estrogens
how does communication in the ZP from granulosa cell to oocyte occur?
through gap junctions, and these gap junctions go away for ovulation
after ovulation, the tertiary follicle granulosa and theca cells _______ and become ______
mix
corpus luteum
which follicle is degenerating, and why?
the left, because the boundaries are not as clear, there is a sort of rough edge look to it
the right one is functional because the boundaries are very clear and it appears way more circular than the left
BUT Ungrin said it’s hard to tell sometimes based on the slide is cut
which side is the corpus luteum and which is the corpus albicans?
the left is the corpus luteum because it is very cellular
the right is the corpus albicans because it is mostly collagen with a few cells
What is this and what are the bubble lookin things?
this is an atretic follicle (degenerating), and those circles are vesicles from the cell breaking down
this is a corpus luteum. what cells are 1 and what cells are 2?
1: granulosa cells, they are bigger
2: theca lutein cells, they are smaller
which is the ampulla, which is the isthmus?
ampulla is the left because it has a lot more surface area, it is ciliated, and it has thinner muscle
isthmus is the right because it has a thicker muscle layer, not ciliated,
label the uterus
A: stratum functional, the part that sloughs off and is shed with menstruation
B: stratum basalis, the part that will regenerate the functionalis
C: endomedtrium
D: myometrium
E: perimetrium
what are ya lookin at son?
canine uterine glands in the endometrium I guess
what is this structure in the uterine wall?
a caruncle
wot in tarnation is this
the cervix, yeehaw
what is this?
vaginal wall in proestrus (thin layer of keratinized cells)
primordial follicle with simple squamous epithelial cells
what is the structure in the red dotted circle?
a primary follicle with simple cuboidal granulosa cells
name the structure
late secondary follicle (stratified cuboidal granulosa, antrum starting to show but incomplete)
granulosa cells
theca cells
zona pellucida
antrum
cumulus oophorus
corona radiata
top left: ampulla
bottom left: isthmus
top right: infundibulum
blue: endometrium
red: stratum functionalis
green: stratum basalis
yellow: myometrium
purple: perimetrium
