GI pathology 5 Flashcards

1
Q

What are polyps?

A
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2
Q

What are the types of intestinal tumors?

A
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3
Q

What are hyperplastic polyps?

A
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4
Q

Dscribe the pathogenesis hyperplastic polyps

A
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5
Q

Do hyperplastic polyps have malignant potential?

A

No

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6
Q

Where do hyperplastic polyps occurs?

A

Usually left colon- descending, sigmoid

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7
Q

What are the sizes of hyperplastic polyps?

A

Less than 5mm in diameter

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8
Q

What are the morphological features of hyperplastic polyps ?

A
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9
Q

What does a hyperplastic polyps look like?

A
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10
Q

What are hamartomatous polyps ?

A
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11
Q

Contrast the types of hamartomatous polyps

A
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12
Q

What are the morphological features of juvenile polyps?

A
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13
Q

At what age does juvenile polyps occur?

A

Children under 5

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14
Q

Where do juvenile polyps occur?

A

Rectum

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15
Q

What are the symptoms of juvenile polyps?

A

Typically present with rectal bleeding & rarely, intussusception

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16
Q

What do juvenile polyps look like?

A
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17
Q

What are the morphological features of Peutz Jegher syndrome?

A
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18
Q

What is Peutz Jegher syndrome?

A
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19
Q

What are the dermatological features of Peutz Jegher syndrome?

A
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20
Q

What location does Peutz Jegher syndrome?

A

Most common in small intesrine

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21
Q

What are the complications of Peutz Jegher syndrome?

A
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22
Q

Why are adenomatous polyps so clinically significant?

A
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23
Q

Describe the epidemiology of adenomatous polyps/ adenomas

A
24
Q

What’s the main recommendation of adenomatous polyps/adenomas?

A
25
Q

What are the histology of adenomas/adenomatous polyps?

A
26
Q

What are the classifications of adenomas/ adenomatous poly0d?

A
27
Q

What are the conventional adenomas? What do adenomas/ adenomatous polyps/adenomas look like?

A
28
Q

Contrast tubular and villus adenoma histology

A
29
Q

What are sessile serrrated adenomas?

A
30
Q

What are the clinical features of adenomas?

A
31
Q

What is familial adenomatous polyposis?

A
32
Q

What is the etiology for familial adenomatous polyposis?

A

APC(adenomatous polyposis coli) tumor suppressor gebe on chr. 15q

33
Q

What’s the diagnosis of FAP?

A

Atleast 100 polyps; mostly tubular in histology

34
Q

Describe the risk of malignancy of FAP

A
35
Q

What are the associated syndromes of Familial adenomatous polyposis ?

A
36
Q

What does APC mean?

A
37
Q

What is HNPCC known as?

A
38
Q

What is the etiology of HNPCC?

A
39
Q

What are the features of colon carcinoma?

A
40
Q

What are the main associations of cancers?

A
41
Q

Give the epidemiology of colorectal carcinoma

A
42
Q

What are the etiopathogenesis of colorectal carcinoma?

A
43
Q

Describe the APC pathway for colorectal carcinoma

A
44
Q

Contrast right sided and left-sided colon cancer

A
45
Q

What does ascending colon adenocarcinoma look like?

A
46
Q

What does circumferential, ulcerated rectal cancer look like?

A
47
Q

What does cancer of the sigmoid colo look like?

A

Only C

48
Q

What does adenocarcinoma look like?

A
49
Q

Contrast the APC and MSI pathway

A
50
Q

What are carcinoids derived from? Where are they often located?

A
51
Q

What is the main epidemiology of carcinoids?

A

Peak incidence in the sixth decade

52
Q

What are the clinical features of neuroendocrine tumors/carcinoids?

A
53
Q

What does a carcinoid/neuroendocrine look like?

A
54
Q

What is gastrointestinal lymphomas?

A
55
Q

Contrast B-cell lymphomas and T-cell lymphomas

A
56
Q

What is MALT

A