GI pathology 5 Flashcards by Jhaunte Braithwaite

Q

What are polyps?

A

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Q

What are the types of intestinal tumors?

A

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Q

What are hyperplastic polyps?

A

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Q

Dscribe the pathogenesis hyperplastic polyps

A

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Q

Do hyperplastic polyps have malignant potential?

A

No

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Q

Where do hyperplastic polyps occurs?

A

Usually left colon- descending, sigmoid

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Q

What are the sizes of hyperplastic polyps?

A

Less than 5mm in diameter

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Q

What are the morphological features of hyperplastic polyps ?

A

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Q

What does a hyperplastic polyps look like?

A

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Q

What are hamartomatous polyps ?

A

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Q

Contrast the types of hamartomatous polyps

A

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Q

What are the morphological features of juvenile polyps?

A

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Q

At what age does juvenile polyps occur?

A

Children under 5

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Q

Where do juvenile polyps occur?

A

Rectum

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Q

What are the symptoms of juvenile polyps?

A

Typically present with rectal bleeding & rarely, intussusception

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Q

What do juvenile polyps look like?

A

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Q

What are the morphological features of Peutz Jegher syndrome?

A

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Q

What is Peutz Jegher syndrome?

A

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Q

What are the dermatological features of Peutz Jegher syndrome?

A

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Q

What location does Peutz Jegher syndrome?

A

Most common in small intesrine

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Q

What are the complications of Peutz Jegher syndrome?

A

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Q

Why are adenomatous polyps so clinically significant?

A

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Q

Describe the epidemiology of adenomatous polyps/ adenomas

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A

Q

What’s the main recommendation of adenomatous polyps/adenomas?

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A

What are the histology of adenomas/adenomatous polyps?

What are the classifications of adenomas/ adenomatous poly0d?

What are the conventional adenomas? What do adenomas/ adenomatous polyps/adenomas look like?

Contrast tubular and villus adenoma histology

What are sessile serrrated adenomas?

What are the clinical features of adenomas?

What is familial adenomatous polyposis?

What is the etiology for familial adenomatous polyposis?

APC(adenomatous polyposis coli) tumor suppressor gebe on chr. 15q

What’s the diagnosis of FAP?

Atleast 100 polyps; mostly tubular in histology

Describe the risk of malignancy of FAP

What are the associated syndromes of Familial adenomatous polyposis ?

What does APC mean?

What is HNPCC known as?

What is the etiology of HNPCC?

What are the features of colon carcinoma?

What are the main associations of cancers?

Give the epidemiology of colorectal carcinoma

What are the etiopathogenesis of colorectal carcinoma?

Describe the APC pathway for colorectal carcinoma

Contrast right sided and left-sided colon cancer

What does ascending colon adenocarcinoma look like?

What does circumferential, ulcerated rectal cancer look like?

What does cancer of the sigmoid colo look like?

Only C

What does adenocarcinoma look like?

Contrast the APC and MSI pathway

What are carcinoids derived from? Where are they often located?

What is the main epidemiology of carcinoids?

Peak incidence in the sixth decade

What are the clinical features of neuroendocrine tumors/carcinoids?

What does a carcinoid/neuroendocrine look like?

What is gastrointestinal lymphomas?

Contrast B-cell lymphomas and T-cell lymphomas

What is MALT