GI pathology 5 Flashcards
What are polyps?
What are the types of intestinal tumors?
What are hyperplastic polyps?
Dscribe the pathogenesis hyperplastic polyps
Do hyperplastic polyps have malignant potential?
No
Where do hyperplastic polyps occurs?
Usually left colon- descending, sigmoid
What are the sizes of hyperplastic polyps?
Less than 5mm in diameter
What are the morphological features of hyperplastic polyps ?
What does a hyperplastic polyps look like?
What are hamartomatous polyps ?
Contrast the types of hamartomatous polyps
What are the morphological features of juvenile polyps?
At what age does juvenile polyps occur?
Children under 5
Where do juvenile polyps occur?
Rectum
What are the symptoms of juvenile polyps?
Typically present with rectal bleeding & rarely, intussusception
What do juvenile polyps look like?
What are the morphological features of Peutz Jegher syndrome?
What is Peutz Jegher syndrome?
What are the dermatological features of Peutz Jegher syndrome?
What location does Peutz Jegher syndrome?
Most common in small intesrine
What are the complications of Peutz Jegher syndrome?
Why are adenomatous polyps so clinically significant?
Describe the epidemiology of adenomatous polyps/ adenomas
What’s the main recommendation of adenomatous polyps/adenomas?
What are the histology of adenomas/adenomatous polyps?
What are the classifications of adenomas/ adenomatous poly0d?
What are the conventional adenomas? What do adenomas/ adenomatous polyps/adenomas look like?
Contrast tubular and villus adenoma histology
What are sessile serrrated adenomas?
What are the clinical features of adenomas?
What is familial adenomatous polyposis?
What is the etiology for familial adenomatous polyposis?
APC(adenomatous polyposis coli) tumor suppressor gebe on chr. 15q
What’s the diagnosis of FAP?
Atleast 100 polyps; mostly tubular in histology
Describe the risk of malignancy of FAP
What are the associated syndromes of Familial adenomatous polyposis ?
What does APC mean?
What is HNPCC known as?
What is the etiology of HNPCC?
What are the features of colon carcinoma?
What are the main associations of cancers?
Give the epidemiology of colorectal carcinoma
What are the etiopathogenesis of colorectal carcinoma?
Describe the APC pathway for colorectal carcinoma
Contrast right sided and left-sided colon cancer
What does ascending colon adenocarcinoma look like?
What does circumferential, ulcerated rectal cancer look like?
What does cancer of the sigmoid colo look like?
Only C
What does adenocarcinoma look like?
Contrast the APC and MSI pathway
What are carcinoids derived from? Where are they often located?
What is the main epidemiology of carcinoids?
Peak incidence in the sixth decade
What are the clinical features of neuroendocrine tumors/carcinoids?
What does a carcinoid/neuroendocrine look like?
What is gastrointestinal lymphomas?
Contrast B-cell lymphomas and T-cell lymphomas
What is MALT
