Anti diabetic Drugs 2 Flashcards by Jhaunte Braithwaite

Q

What drugs are considered oral hypoglycemics?

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Q

What are the sulfonylureas? What’s the MOA?

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Q

Describe chloropropamide as a sulfonylurea

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Q

When is chlorpropamide contraindicated?

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Q

What are the second generations sulfonylureas?

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Q

What should we be Caucasus of glyburide?

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Q

Describe glipizide

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Q

Whaat is glimepiride?

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Q

What is the pharmacokinetics of second generation of sulfynourea ?

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Q

What are the uses of second generation sulfonylureas?

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Q

What are the adverse effects of second generation sulfonylurea?

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Q

What are meglitinides (glinides)?

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Q

What are the uses of meglitinides (glinides)?

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Q

What are the adverse effects of meglitinides(glinides)?

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Q

What are biguanides?

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Q

What’s the MOA of biguanides?

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Q

What are the adverse effects of biguanides?

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Q

What are the other uses of biguanides (metformin?)?

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Q

What are the MOA of thiazolidibediones (TZDs, Glitazones)

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Q

What are the adverse effects of thiazolidibediones (TZDs, glitazones)?

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Q

What are the other uses of thiazolidinediones (TZDs, glitazones)?

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Q

What are a-Glucosidase inhibitors?

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Q

Describe the MOA of a-glocosidase inhibitors?

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Q

What are the adverse effects and contraindications of a-glucosidase inhibitors ?

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Q

Describe incretin analogs: exenatide

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Q

Describe the adverse effects of incretin analogs exenatide

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Q

Describe inhibitors of DPP-IV: Sitagliptin

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Q

Describe the adverse effects of inhibitors of DPP-IV: Stitagliptin

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Q

Describe analogs of amylin: pramlintide

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Q

Describe the adverse effects of amylin: pramilinitide

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Q

Describe Bile-acid sequestration: colesevelam

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Q

Describe the adverse effects of Bile-acid sequestrants: colesevelam

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Q

Describe SGLT2 Inhibitors: canaglifozin

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Q

Describe the adverse effects of SGLT2 Inhibitirs : Canagliflozin

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Q

What are the pros and cons of metformin? How does this affect insulin?

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Q

Describe the pros and cons of sulfonylureas and insulin effect

A

Q

Describe the pros and cons of meglitinides and insulin effects

A

Q

Describe glitazones pros and cons + insulin effects

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Q

Describe the pros and cons of a-glucosidase inhibitirs + insulin effects

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Q

Describe the pros and cons of exenatide and insulin effects

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Q

Describe the pros and cons of pramlinitide and insulin effects

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Q

Describe the pros and cons of Sitagliptin and insulin effects

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Q

Describe the pros and cons of Colesevelam and it’s insulin effects

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Q

Describe the pros and cons of Canagliflozin and it’s insulin effects

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Q

Describe the pros and cons of insulin and it’s insulin effects

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Q

Describe the management of diabetes

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Q

Describe initial drug therapy of type 2 diabetes

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Q

How do we advance to dual combination therapy of type 2 diabtes?

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Q

How do we advance to triple combination therapy in type 2 diabetes ?

A

Q

How do we transition to insulin therapy?

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Q

How do we transition to insulin therapy in diabetes type 2?

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Q

Describe the management of diabetes in pregnancy

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Q

Describe the use of insulin in pregnancy

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Q

What anti diabetic drugs are used in pregnancy?

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Q

How can we prevent & manage hypertension?

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Q

How can we prevent & manage Dyslipidemia?

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Q

How can antiplatelet agents be used for diabetic complications?

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Q

How do we manage abd prevent diabetic nephropathy?

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Q

How do we prevent and treat diabetic neuropathy?

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Q

What is gastropareisis?

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Q

Describe erectile dysfunction and How it’s treated

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Q

Describe foot care for diabetics

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Q

What is glucagon?

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Q

What are the metabolic effects of glucagon?

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Q

What are the glucagon effects on heart muscle?

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Q

What are the effects of glucagon on smooth muscles?

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Q

What are the uses of glucagon?

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Q

What are the adverse effects of glucagon?

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