Adrenocorticosteroids Flashcards

1
Q

What are the layers of the adrenal cortex ?

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2
Q

What hormones are made up of each layer?

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3
Q

What are the classifications of corticosteroid agonists & antagonists?

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4
Q

What are the glucocorticoids?

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5
Q

What are the synthetic glucocorticoids?

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6
Q

What is the mechanism of action of glucocorticoids?

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7
Q

What are the pharmacokinetics of hydrocortisone?

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8
Q

How are glucocorticoids administered?

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9
Q

Describe circadian control of cortisol

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10
Q

What are the organ & tissue effects of glucocorticoids?

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11
Q

What are the metabolic effects of glucocorticoids?

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12
Q

What are the immunosuppressive effects of glucocorticoids?

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13
Q

What are the anti-inflammatory effects of glucocorticoids?

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14
Q

What effects do glucocorticoids have on the ps6chology, neurology, PUD risk, and lung/hematology of a person?

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15
Q

What are the adverse effects of glucocorticoids?

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16
Q

How do we minimize the adverse effects of glucocorticoids?

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17
Q

How do we minimize adverse effects of glucocorticoids?

18
Q

What are the main mineralcorticoids?

19
Q

What’s the MOA of mineralcorticoids?

20
Q

What are the major effects of mineralcorticoids?

21
Q

What are the adverse effects of mineralcorticoids?

22
Q

Contrast anti-inflammatory and salt-retaining effects of glucocorticoids and mineralcorticoids

23
Q

What are the principles of treatments of mineralcorticoids?

24
Q

What are the categories of clinical applications of corticosteroids?

25
Q

How do we treat chronic adrenal insufficiency?

26
Q

How do we treat acute adrenal insufficiency?

27
Q

How do we treat congenital adrenal hyperplasia?

28
Q

What are the clinical applications of Cushing’s syndrome?

29
Q

How do we treat Cushing’s syndrome?

30
Q

What fetal lung maturation? How is it treated?

31
Q

What are the non-adrenal disorders clinical applications?

32
Q

Describe classification of corticosteroid agonists & antagonists

33
Q

What are the main corticosteroid receptor antagonists?

34
Q

What’s the MOA and clinical applications of mifepristone?

35
Q

What are the MOA and clinical applications of spironolactone?

36
Q

What are the treatments and clinical applications of aldosteronism?

37
Q

What are the adverse effects of spironolactone?

38
Q

What are the synthesis inhibitors?

39
Q

Describe Ketoconazole MOA and clinical applications

40
Q

What are the adverse effects of ketoconazole?

41
Q

Describe MOA and clinical applications of Aminoglutethimide

42
Q

Describe MOA and clinical application and Adverse effects of metyrapone