Gastroinfections 1 Flashcards
What causes microbiota variation?
What are the factors possibly leading to esophagitis?
What’s the clinical presentation of esophagitis?
How do we diagnose candida?
Describe the candida spp.
How can we identify candida among other yeasts?
How can we diagnose candida?
What are the biological features of HSV-1 (HHV-1)?
What is HSV-1(HHV-1)?
What’s the genome of HSV-1/HHV-1?
Large, enveloped dsDNA virus
Describe the diagnosis of HSV-1/HHV-1
What is cytomegalovirus?
How can we diagnose CMV?
Summarize how different viruses present in endoscopy
What is gastritis?
What is H. Pylori known for?
What are the biological factors of H. pylori?
What are ALL the H. pylori virulence factors to colonize?
What are ALL the virulence factors of H. pylori for disease induction?
What are ALL the virulence factors of H. pylori for immune escape?
What are the strain specific factors virulence factors of H. pylori that risk PUD & Oncogenes?
What is the main virulence factor for immune escape in H. Pylori?
Lipopolysaccharides- low immunogenicity
What virulence factors of H. pylori cause disease induction?
-Type IV secretion system- injection of effectors
-secretory enzymes
-exptoxins
-effectors
What main virulence factors of H. pylori lead to colonization?
Adhesins- BabA & SabA
Outer membrane proteins
Flagella- bacterial movement to epithelial surface
Urease- neutralize gastr8c acid
What does urease do in H. pylori?
Urease- neutralize gastr8c acid
How does H. Pylori increase risk 9f cancer?
Oncoprotein- causes signaling alternations- changes host physiology
Facilitates malignant transformation of gastric epithelial cells
What allows H. pylori to survive in the stomach?
Urease
What virulence factors of H. pylori lead to tissue damage ?
CagA, VacA exotoxin, enzymes
Contrast peptic ulcer disease in gastric ulcer and duodenal ulcer
Describe potential outcomes of H. pylori
What Noninvasive tests diagnose H. Pylori ?
What are the invasive Tests for H. pylori diagnosis?
Describe the urease breath test to diagnose H. Pylori
Describe the fecal antigen test to diagnose H. Pylori
Describe serology of H. pylori as a diagnostic test
What are the invasive tests f9r H. pylori?
Describe the principle of urease test
What are the major players of the abdominal cavity?
What are the main infections of the abdominal cavity?
Describe the clinical presentation of the bacterial peritonitis
Where is spontaneous bacterial peritonitis usually seen? What usually cases it?
What is secondary bacterial peritonitis?
What’s the clinical presentation of appendicitis?
Describe the pathogenesis of appendicitis
Describe the clinical presentation of pancreatitis