Gastrointestinal Drugs 2 Flashcards

1
Q

What are the therapies for disorders of the lower GI Tract?

A
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2
Q

What are the types laxatives ?

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3
Q

Describe constipation

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4
Q

Describe the etiology of constipation

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5
Q

What’s the first-line strategy for constipation?

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6
Q

What are the bulk-forming laxatives? What do they do?

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7
Q

What are Cathertics(laxatives)?

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8
Q

Describe caster oil as a laxative

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9
Q

What do use as stool softeners?

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10
Q

Describe lubricant laxatives

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11
Q

Describe osmotic laxatives

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12
Q

Describe polyethylene glycol as an osmotic laxative

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13
Q

Describe lubiprostone

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14
Q

What are the adverse efffects of lubiprostone?

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15
Q

What are the selective Mu-opioid receptor antagonists?

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16
Q

What are the opioid agonists?

A
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17
Q

How do opioid agonists aid for anti diarrheal drugs?

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18
Q

How can Ocreotide act as an anti diarrheal drug?

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19
Q

What are the indications of Octreotide?

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20
Q

What are the adverse effects of octreotide?

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21
Q

Describe Bismuth compounds as anti diarrheal

A
22
Q

What is irritable bowel syndrome ?

A
23
Q

Describe the first-line treatment of irritable bowel syndrome

A
24
Q

What do we use constipation predominant IBS?

A
25
Q

How do we use diarrhea predominant IBS?

A
26
Q

Give an overview of inflammatory bowel disease

A
27
Q

What do we use to guide IBD ?

A
28
Q

Describe the mild category of IBD

A
29
Q

Describe moderate to severe disease of IBD

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30
Q

Describe the severe-fulminant disease of IBD

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31
Q

Give an overview of how we treat different severities of IBD

A
32
Q

Describe Aminosalicylates that are used to treat IBD

A
33
Q

Describe describe the MOA theories of aminosalicylates to treat IBD

A
34
Q

Describe the treatment of Aminosalicylates for IBD

A
35
Q

How does sulfasalzine work?

A
36
Q

What is sulfasalzine used for?

A
37
Q

What are the adverse effects of Aminosalicylates?

A
38
Q

Describe the use of balsalazide as Aminosalicylates

A
39
Q

Describe mesalamine as aminosalicylates

A
40
Q

How are glucocorticoids used for IBD? MOA

A
41
Q

How are glucocorticoids used to treat IBD? MOA

A
42
Q

How are glucocorticoids used to treat IBD? MOA

A
43
Q

How can prednisone and prednisolone be used to treat IBD?

A
44
Q

What are the adverse effects of prednisone & prednisolone?

A
45
Q

How is budnesone used to treat IBD?

A
46
Q

Describe Immunosuppresants used to treat inflammatory bowel disease

A
47
Q

What are the adverse effects of immunosuppressants?

A
48
Q

Describe Allopurinol

A
49
Q

Describe the methotrexate

A
50
Q

Describe the adverse effects of methotrexate

A
51
Q

Describe the cyclosporine

A
52
Q

Describe the adverse effects of cyclosporine?

A