Gastrointestinal Drugs 1 Flashcards
What categories of drugs do we use to treat gastroesophagewl reflux & peptic ulcer disease?
What factors impact acid peptic disorders?
Describe gastroesophageal reflux disease
What are the symptoms of gastroesophageal reflux ?
Describe the complications of gastroesophageal reflex
What is peptic ulcer disease?
What are the two major physiological states of gastric acid production?
What’s the purpose of Antacids?
What are the common antacids and their side effects?
What are the drug interactions of Antacids?
How do H2 receptor antagonists treat Gastroesophageal reflux & peptic ulcer disease?
Describe the time of onset, duration of action, & tachyphylaxis of H2 receptor antagonists
What H2 receptor antagonists are used to treat gastroesophageal reflux & peptic ulcer disease?
What impact does H2 receptor antagonisms have on physiology?
What are the indications of H2 receptor antagonists?
What are the adverse effects of H2 receptor antagonists ?
Describe proton pump inhibitors usage
Describe the effects of PPIs on gastric acid secretion
What are drug names of PPIs?
Describe the indications of PPIs
Describe the adverse effects of PPI
Describe PPI and CYP450 interactions
Describe the properties of H. pylori
Describe the eradication of H. pylori
What is Misoprostol?
Describe the properties of misoprostol
What is sucralfate?
What are the properties of Bismuth Subsalicylate?
Describe the adverse effects of bismuth subsalicylate
What are the treatments of disorders of Upper GI tract?
What are the types of prokinetic drugs?
Describe the properties of prokinetic agents
Describe erythromycin
Describe Cisapride
What are the prokinetic agents?
Erythromycin & cisapride
Describe the properties of metoclopramide
What are the indications of metoclopramide?
What are the adverse effects of Metoclopramide?
What are the anti-emetic drugs?
What are the molecular targets of the vomitting reflex?
How do chemotherapy induce nausea and vomitting(CINV)?
What antimuscuranic can be used for anti-emetics?
Describe the H1 antagonists can be used as anti-emetics
Describe Promethazine as an anti-emetic
Describe Droperidol of anti-emetics
Describe 5-HT3 Antagonists
How can corticosteroids be used as anti-emetics?
How can Neurokinin 1 (NK1) Antagonists?
How can benzodiazepines one used as anti-emetics?
What are the adverse effects of benzodiazepines?
CNS depression and dependence
How can cannabis be used as an anti-emetic?
Describe the adverse effects of Cannaboids