Gastrointestinal Drugs 1 Flashcards

1
Q

What categories of drugs do we use to treat gastroesophagewl reflux & peptic ulcer disease?

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2
Q

What factors impact acid peptic disorders?

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3
Q

Describe gastroesophageal reflux disease

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4
Q

What are the symptoms of gastroesophageal reflux ?

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5
Q

Describe the complications of gastroesophageal reflex

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6
Q

What is peptic ulcer disease?

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7
Q

What are the two major physiological states of gastric acid production?

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8
Q

What’s the purpose of Antacids?

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9
Q

What are the common antacids and their side effects?

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10
Q

What are the drug interactions of Antacids?

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11
Q

How do H2 receptor antagonists treat Gastroesophageal reflux & peptic ulcer disease?

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12
Q

Describe the time of onset, duration of action, & tachyphylaxis of H2 receptor antagonists

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13
Q

What H2 receptor antagonists are used to treat gastroesophageal reflux & peptic ulcer disease?

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14
Q

What impact does H2 receptor antagonisms have on physiology?

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15
Q

What are the indications of H2 receptor antagonists?

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16
Q

What are the adverse effects of H2 receptor antagonists ?

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17
Q

Describe proton pump inhibitors usage

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18
Q

Describe the effects of PPIs on gastric acid secretion

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19
Q

What are drug names of PPIs?

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20
Q

Describe the indications of PPIs

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21
Q

Describe the adverse effects of PPI

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22
Q

Describe PPI and CYP450 interactions

A
23
Q

Describe the properties of H. pylori

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24
Q

Describe the eradication of H. pylori

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25
Q

What is Misoprostol?

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26
Q

Describe the properties of misoprostol

A
27
Q

What is sucralfate?

A
28
Q

What are the properties of Bismuth Subsalicylate?

A
29
Q

Describe the adverse effects of bismuth subsalicylate

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30
Q

What are the treatments of disorders of Upper GI tract?

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31
Q

What are the types of prokinetic drugs?

A
32
Q

Describe the properties of prokinetic agents

A
33
Q

Describe erythromycin

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34
Q

Describe Cisapride

A
35
Q

What are the prokinetic agents?

A

Erythromycin & cisapride

36
Q

Describe the properties of metoclopramide

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37
Q

What are the indications of metoclopramide?

A
38
Q

What are the adverse effects of Metoclopramide?

A
39
Q

What are the anti-emetic drugs?

A
40
Q

What are the molecular targets of the vomitting reflex?

A
41
Q

How do chemotherapy induce nausea and vomitting(CINV)?

A
42
Q

What antimuscuranic can be used for anti-emetics?

A
43
Q

Describe the H1 antagonists can be used as anti-emetics

A
44
Q

Describe Promethazine as an anti-emetic

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45
Q

Describe Droperidol of anti-emetics

A
46
Q

Describe 5-HT3 Antagonists

A
47
Q

How can corticosteroids be used as anti-emetics?

A
48
Q

How can Neurokinin 1 (NK1) Antagonists?

A
49
Q

How can benzodiazepines one used as anti-emetics?

A
50
Q

What are the adverse effects of benzodiazepines?

A

CNS depression and dependence

51
Q

How can cannabis be used as an anti-emetic?

A
52
Q

Describe the adverse effects of Cannaboids

A