Gestational Pathology 1 Flashcards

1
Q

What is the most common site of ectopic pregnancy and what is the most important risk factor for?

A

Lumen of Fallopian tube

Scarring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What two conditions can lead to scarring which would put the patient at risk for ectopic pregnancy?

A

Endometriosis and PID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the classic presentation for ectopic pregnancy?

A

Woman presents with lower abdominal quadrant pain weeks after missed period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

When do spontaneous abortions occur and what are the 3 things a women will present with?

A

Before 20 weeks

Vaginal bleeding, cramp like pain, and passing of fetal tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Most common cause of of abortion?

A

Chromosomal anomalies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is placenta Previa and how does it present?

A

Where the placenta implants in the lower uterus and blocks part or all of the cervical os.
Third trimester bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is placenta abruption?

A

When the placenta abruptly detaches from the uterine wall.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

2 clinical presentations of placenta abruption?

A

Third trimester bleeding and fetal insufficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Placental abruption is a common cause of what?

A

Still birth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is placenta accreta?

A

When the placenta implants to implants all the way into the myometrium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are 2 complications of placenta accreta and what does it often require?

A

Very difficult to deliver the placenta, so it often stays
Staying causes post partum bleeding

Requires hysterectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is preeclampsia?

A

Pregnancy induced HTN, proteinuria, and edema usually presenting in 3rd trimester

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the cause of preeclampsia?

A

Maternal-fetal vascular interface in the placenta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What can be found in the placental blood vessels of a women with preeclampsia?

A

Fibrinoid necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is eclampsia?

A

Preeclampsia with seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a complication of preeclampsia?

A

HELLP

Hemolysis, elevated liver enzymes, low platelets

17
Q

What are 3 risk factors for sudden infant death syndrome?

A

Sleeping on stomach, exposure to cigarette smoke and prematurity

18
Q

What is a hydatidiform mole?

A

Abnormal conception that causes the villi to be swollen and edematous with proliferation of the trophoblastic surrounding the villi

19
Q

What effect does this have on the uterus?

A

Uterus is much larger than the gestational date and the beta hCG is much higher as well.

20
Q

How are these moles diagnosed, what are the two ways we can find them?

A

Well, if the lady does not have prenatal care, then she will begin passing the moles out of the vaginal canal in the early second trimester.
If she does have prenatal care, then they will be diagnosed on ultra sound. Fetal heart sounds absent along with the snow storm appearance.

21
Q

What are the two classifications for moles?

A

Partial or complete

22
Q

What are the 4 criteria I am asking to classify a mole to be partial or complete?

A

Genetics
Fetal tissue
Villus edema
Trophoblastic proliferation

23
Q

What is the specific criteria of those 4 things for a complete mole?

A

Empty ovum fertilized by two sperms giving 46 chromosomes
Fetal tissue is absent
All villi are edematous
Completely covered by trophoblastic proliferation

24
Q

Which one has a higher risk for choriocarcinoma

A

Complete mole

25
Q

Which mole has a higher level of beta hCG and why?

A

Complete mole because beta hCG comes from syncytiotrophoblast and there is more proliferation in a complete mole.

26
Q

Choriocarcinoma is a tumor of what type of cells?

A

Trophoblast cells

27
Q

What are absent with a choriocarcinoma?

A

Bill are absent

28
Q

What are the two pathways that lead to a choriocarcinoma and what is the main difference for purposes of exams?

A

Sporadic germ cell pathway and being a complication of gestation.
Gestational pathway choriocarcinoma responds well to chemotherapy and sporadic pathway ones do not.