Genitourinary Medications

Question 1

SILDENAFIL, VARDENAFIL

1. Indications
2. MOA
3. SEs and contraindications
4. Other

Answer 1

1. Erectile dysfunction
2. cGMP (relaxes smooth muscle in penis during erection) is broken down by PDE-5
   Drugs inhibit PDE-5
3. Cyanopsia
   Photosensitivity
   Flushing and headaches

Question 2

PRAZOIN, TERAZOSIN, TAMSULOSIN

1. Indications
2. MOA
3. SEs and contraindications
4. Other

Answer 2

1. Benign prostatic hyperplasia
2. a1 blocker: relaxes smooth muscle in the bladder and prostate, thereby decreasing urinary outflow obstruction in men with BPH.
3. First dose hypotension
   Tamsulosin: floppy iris syndrome