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Gen Pharm > Cell Wall Synthesis Blockers > Flashcards

Cell Wall Synthesis Blockers Flashcards

1
Q

Bacitracin inhibits ________
Penicillins/cephalosporins inhibit _______

A

Peptidoglycan, transpeptidase

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2
Q

BACITRACIN

  1. Indications
  2. MOA
  3. SEs and contraindications
  4. Other
A
  1. gram (+) bacteria (S. Aureus
    Blepharitis
  2. inhibits transfer of peptidoglycans of the cell wall
  3. Blurry vision (ointment)
  4. N/A
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3
Q

Polysporin combination:

A

Bacitracin + polymyxin B

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4
Q

Neosporin combination:

A

Neomycin + bacitracin + polymyxin B

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5
Q

AMOXICILLIN/DICLOXACILLIN

  1. Indications
  2. MOA
  3. SEs and contraindications
  4. Other
A
  1. Gram (+) and gram (-) coverage from amoxicillin
    Syphillis (Pen G),
    Dacryosystitis
    Bacterial infections of the eyelid (hordeola, preseptal cellulitis)
  2. Inhibits transpeptidase
  3. Hypersensitivity reactions (type I and IV)
    Steven Johnson Syndrome
  4. DIcloxacillin is penicillinase resistant (DOC for methicillin sensitive Staph infections (MSSA))
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6
Q

Augmentin combination:

A

Amoxicillin + clavulanic acid

*Amoxicillin used with clavulanic acid due to amoxicillin not being penicillinase resistant

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7
Q

Penicillins have a ___ -member beta lactam ring, and cephalosporins have a ___- member beta lactam ring

A

5, 6

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8
Q

Cephalosporins:

1st gen: ___
2nd gen: ___
3rd gen: ___
4th gen: ___

A
  1. Cephalexin
  2. Cefuroxime
  3. Ceftriaxone and Ceftazidime
  4. Cefepime
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9
Q

CEPHALEXIN/CEFUROXIME (1st gen)

  1. Indications
  2. MOA
  3. SEs and contraindications
  4. Other
A
  1. Gram (+) coverage
    Skin infections (dacryoadenitis, dacryocystitis, preseptal cellulitis
  2. Inhibits transpeptidase
  3. Hypersensitivity reactions

CI in PATIENTS TAKING WARFARIN (alters absorption of vitamin K and can result in excess thinning of the blood)

  1. N/A
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10
Q

CEFTRIAXONE/CEFTAZIDIME (3rd gen)

  1. Indications
  2. MOA
  3. SEs and contraindications
  4. Other
A
  1. Gram (+) and gram (-) coverage
    Bacterial infections (gonorrhea)
    DOC for gonococcal conjunctivitis and orbital cellulitis
  2. Inhibits transpeptidase
  3. Hypersensitivity reactions

CI in PATIENTS TAKING WARFARIN (alters absorption of vitamin K and can result in excess thinning of the blood)

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11
Q

CEFEPIME (4th gen)

  1. Indications
  2. MOA
  3. SEs and contraindications
  4. Other
A

1.Skin infections (dacryoadenitis, dacryocystitis, preseptal cellulitis

  1. Inhibits transpeptidase
  2. Hypersensitivity reactions

CI in PATIENTS TAKING WARFARIN (alters absorption of vitamin K and can result in excess thinning of the blood)

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Gen Pharm (17 decks)

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