Dermatologic Medications

Question 1

ISOTRENTINOIN (Accutane)

1. Indications
2. MOA
3. SEs and contraindications
4. Other

Answer 1

1. Acne
2. Reduces size and degree of oil production from sebaceous glands
3. Blepharoconjunctivitis
   Dry eye
   IIH
   Lid edema
   Loss of color vision
   Nyctalopia
   CI: pregnancy (teratogenic)

Question 2

METRONIDAZOLE

1. Indications
2. MOA
3. SEs and contraindications
4. Other

Answer 2

1. Acne rosacea
2. Disrupts DNA and inhibits nucleic acid synthesis: anti-inflammatory properties
3. Irritation of the skin and eyes