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My2 dermatology > general microbiology > Flashcards

general microbiology Flashcards

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Dermatology Board Prep flashcards
1
Q

what does adhesion mean for a bacteria

A

ability to bind to host

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2
Q

what does invasin mean for a bacteria

A

ability to penetrate cell/ host tissue

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3
Q

what does impedin mean for a bacteria

A

avoiding host defence

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4
Q

what does aggresin mean for a bacteria

A

how it directly damages hosts

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5
Q

what does modulin mean for a bacteria

A

indirect damage to host

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6
Q

what are adhesins

A

ECM molecules on epithelial cells

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7
Q

name competitive bacterial flora

A

staph epi, corynebacterium (diptheroids), propionibacterium

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8
Q

give an example of coagulase +ive staph

A

staph A (wound and skin infection) - golden

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9
Q

give an example of coagulase -ive staph

A

staph epidermis

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10
Q

is staph anaerobic or aerobic and what does it look like

A

aerobic but can be aerobic, gram +ive cocci clusters

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11
Q

where is staph A normally found in humans

A

nasal mucosa

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12
Q

what is the best antibiotic for staph A

A

fluclox

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13
Q

what are virulence factors of Staph A

A

fibrogen binding protein, TSST1, PVL

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14
Q

what does TSST1 toxin do

A

release large amounts of interleukins and chemokines

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15
Q

what does PVL toxin do

A

kills white blood cells

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16
Q

what is MRSA and how do you treat it

A

highly contagious strain resistant to methilin - treat doxy, co-trimoxazole, clinda, vanco

17
Q

what skin conditions does staph A

A

cellulitis, infected eczema, impetigo

18
Q

what serious conditions can staph cause

A

toxic shock (TTST1), scalded skin syndrome (TTST1), necrotistising fasciitis (PVL), recurrent furnuclosis (PVL), necrotising pneumonia (PVL)

19
Q

what are the symptoms of toxic shock syndrome

A

high fever, diffuse macular rash and erythema, hypotension, V+D, sore throat, causes huge release of chemokines

20
Q

what is a common skin commensal

A

staph epidermis

21
Q

give an example of alpha/ partial haemolytic stress

A

strep pneumonia and strep viridans (endocarditis) - partial

22
Q

give an example of beta haemolytic stress

A

GAS eg strep (throat and skin) pyogenes, group B eg neonatal meningitis, group C, G etc - complete

23
Q

give an example of gamma haemolytic stress

A

enterococcus, UTI’s and commensals

24
Q

what do GAS organisms cause

A

infected eczema, cellulitis, necrotising fasciitis

25
Q

how do you treat GAS organisms

A

topical or oral penicllin

My2 dermatology (20 decks)

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