Gametogenesis Problems Flashcards
0
Q
What becomes increasingly frequent after age 35?
A
Chromosomal abnormalities increase
- due to lengthy dormant period for the primary oocyte
1
Q
What is the ideal maternal age for reproduction?
A
18-35
2
Q
What is nondisjunction?
A
Failure of homologous chromosomes to separate during meiosis
- occurs in either meiotic divisions - resultant gamete may have 24 or 22 chromosomes
3
Q
What is trisomy?
A
Zygote having 47 chromosomes
- results from union of gametes having 24 and 23 chromosomes - most common is trisomy 21 (Down Syndrome)
4
Q
What is Monosomy?
A
Zygote having 45 chromosomes
- results from union of gametes having 22 and 23 chromosomes - Turner Syndrome (45, X) is only monosomy compatible with life