Gamete Formation and Errors in Meiosis Flashcards

1
Q

What is meiosis

A

The process where sex cells are produced (haploid) and typically there are 4 daughter cells

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2
Q

Spermatogenesis

A

The process of sperm production in testes

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3
Q

Oogenesis

A

the process of ova (egg) formation in the ovaries

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4
Q

What are the parent cells called during spermatogenesis

A

spermatogonia

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5
Q

What are the parent cells called during oogonium

A
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6
Q

What is the end product of spermiogenesis

A

4 haploid gametes (sperm)

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7
Q

What is the end product of oogenesis

A

One haploid gamete (ovum)

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8
Q

Why is only one ovum/egg produced?

A

This is because of the uneven division of cytoplasm during cell division. Polar bodies are the smaller parts of the cytoplasm failing to become a daughter cell as they will degenerate only leaving one ovum.

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9
Q

What methods help achieve genetic variation

A

Independent assortment and crossing over

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10
Q

Independent assortment

A

Metaphase- homologous pairs lined up on equator. In each pair, the maternal and paternal chromosomes will be pulled to different poles of the cell

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11
Q

Crossing over

A

while homologous chromosomes are lined up during prophase 1, non-sister chromatids of homologous pairs may exchange pieces of chromosomes

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12
Q

What are the two types of chromosomal error(mutations) that can occur during meiosis

A

1.changes in chromosome structure
2.changes in chromosome number

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13
Q

Changes in chromosome structure

A

Can happen from crossing over. The chemical bonds that hold the DNA together are broken, and may not reform correctly.

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14
Q

Deletion

A

a piece of a chromosome is deleted

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15
Q

Duplication

A

a section of a chromosome appears two or more times in a row

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16
Q

Inversion

A

a section of a chromosome is inverted

17
Q

Translocation

A

a segment of one chromosome becomes attached to a different chromosome

18
Q

What genetic disorder is caused by deletion

A

Cri du Chat (deletion of chromosome 5)

19
Q

what genetic disorder is caused by duplication

A

Charcot-Marie-Tooth disease (duplication of chromosome 17)

20
Q

what genetic disorder is caused by inversion

A

FG syndrome (inversion of a section of the X chromosome) - mostly in males

21
Q

what genetic disorder is cause by translocation

A

Chronic Myelogenous Leukemia (translocation between chromosomes 9-22)

22
Q

Non-disjunction

A

when homologous chromosomes or sister chromatid do not sperate as they should. Typically occurs in anaphase 1 or 2

23
Q

Monosomy

A

a condition in which one chromosome is lost due to non-disjunction

24
Q

Trisomy

A

a condition where there is a gain of an extra chromosome due to non-disjunction

25
Q

What syndrome is trisomy 21

A

Down syndrome

26
Q

What syndrome is trisomy 18

A

Edward syndrome

27
Q

What syndrome is trisomy 13

A

Patau syndrome

28
Q

What syndrome is XXY

A

Klinefelter syndrome