Fungi and Parasite Intro Flashcards
Unicellular fungi:
multicellular colonies:
Yeast –>reproduce through budding
Mold–>reproduce through spores
threadlike branching , cylindrical tubules, fungal growth. _________ when buds don’t separate
Hyphae,
pseudohyphae
Can grow as either yeast or mold depending on environment
dimorphic fungi
drugs that bind to ergosterol and punch holes in fungal CELL MEMBRANE
amphotericin B &
nystatin
-azole
topical antifungal
essential sterol in fungi
ergosterol
innermost layer around cytoplasm–conatins sterols
Cell Membrane
surrounds cell membrane–mostly carb and proteins
Cell Wall–antigenic to humans
polysaccarides coating surround cell wall
capsule
Catagorzation by skin depth (4)
- superficial
- cutaneous (skin, hair, nails)
- subcutaneous (in soil–gain entrance through skin trauma)
- systemic (dimorphic–inhaled spores–may cause pneumonia)
oral candidiasis aka
thrush (babies normal)
ringworm aka
tinea corporis
nail fungus
tinea unguium
Parasites:
- unicellular
- multicellular
-protozoa
-helminths, insects, arachnids
(sexual and asexual forms)
Malaria–> liver
Plasmodium–4 species
- sexual phase in mosquito
- asexual phase in humans
most widely distributed malaria
Plasmodium vivax
Malaria symp progression
- Hot–destruction of RBCs
- Cold–
- Wet
kitty litter and pregnant women
Toxoplasmosis–uncooked meat and cat feces (from rodents)
Flask-like ULCERS, traveler’s diarrhea (bloody), liver abseses
Amebiasis
profuse watery “greasy” diarrhea, cysts or trophozoites (in stool)
Giardiasis–Stool study or blood test
EXPLOSIVE profuse watery diarrhea 1-2 weeks post exposure, fecal-oral
Cryptosporidium–stool studies, acid-fast
Parasitic worms:
Round worms:
Flat worms:
Helminths:
nematodes
platyhelminthes
worm more common in tropical climates, matures in soil,
Whipworm–trichuris trichiura–stool test for eggs
Pinworm–famales transmit eggs to anus at night–anal itching
Enterobius vermicularis–dx anal cellophane tape detects ova
eggs mature in soil, penetrate skin, larva to gut, tropical areas, anemia,
Hookworm–dx eggs
parasite inhabit PORTAL VASCULAR SYSTEM
Schistosoma– symp: abdominal pain, diarrhea, hepatomegaly, hematuria
eggs released into water, eggs in stool, Viatmin B12 deficiency
Fish Tapeworm–Diphyllobothrium Latum