FTM 47 - Connective Tissue 2 Flashcards
What are the four primary functions of ground substances?
What are the GAGs we need to know?
What component(s) of ground substance have a bottle-brush like structure?
Several gags bound to and stickout from a protein core (making a proteoglycan).
What are the four proteoglycan “bottle-brush” cores we need to know?
Aggrecan, decorin, versican, syndecan
Describe the classification system for the varius types of connective tissues.
What type of tissue is this?
Mucous connective tissue
Describe the basic composition of mucous connective tissue and where it is most commonly found.
What type of tissue is this?
Loose areiolar connective tissue
What is the primary function of loose areolar connective tissue? Describe this tissue’s basic structure and pliability.
What type of tissue is this? Label the marked structures.
Loose connective tissue
From top to bottom: Mast cell, collagen fiber, elastic fiber
What type of tissue is this?
Dense irregular connective issue
Describe the basic structure, function, and loacalization of dense irregular connective tissue.
What type of tissue is this?
Dense regular connective tissue
Describe the basic structure, function, and localization of dense regular connective tissue.
Define endotendineum, peritendineum, epitendineum
What type of tissue is this?
Reticular connective tissue
What are reticular cells and what is their role in reticular connective tissue?
A reticular cell is a type of fibroblast that synthesizes collagen alpha-1(III) and uses it to produce reticular fibers
What is reticular connective tissue often the framework for?
Myeloid (bone marrow) and lymphoid (lymph nodes, spleen) organs.
What type of tissue is this?
Elastic connective tissue
What are the connective tissue disorders that we need to know?
Ehlers-Danlos Syndrome
Fibrosis
Keloids
Scurvy
Marfan’s Syndrome
What is thought to cause Ehlers-Danlos syndrome and how is characterized.
What is a fibrosis/keloid and give examples of both.
Why is vitamin C essential to collagen synthesis?
Ascorbate (vitamin C) is essential for the hydroxylation of proline into hydroxyprolin - a major component of collagen.
What is Marfan’s Syndrome? What causes it and what is its inheritance pattern?
What is anaphylactic shock on a cellular level?
A massive increase in histamine release by mast cells
