Final: psychotic meds

Question 1

what are the psychotic disorders

Answer 1

• schizophrenia
• mania
• acute psychosis

Question 2

what are positive symptoms of psychotic disorders

Answer 2

• hallucinations
• delusions
• racing thoughts

Question 3

what are the negative symptoms of psychotic disorders

Answer 3

• apathy
• lack of emotion
• poor or nonexistant social functioning

Question 4

how to promote adherence with psychotic disorders

Answer 4

• ensure med is taken
• encourage family members to oversee med for outpatients
• use an intramuscular depot prep for long term therapy

Question 5

Haloperidol (haldol) MOA

Answer 5

block receptors for dopamine in the CNS

Question 6

Haloperidol (haldol) class

Answer 6

1st gen antipsychotic

Question 7

Haloperidol (haldol) use

Answer 7

• schizophrenia
• acute psychosis
• tourette’s syndrome

Question 8

Haloperidol (haldol) SE

Answer 8

• serious movement disorder (extrapyramidal symptoms)
• neuroendocrine effects
• prolonged QT interval
• dysrhythmias
• sleep problems

Question 9

Risperidone (risperdal) class

Answer 9

2nd gen antipsychotic

Question 10

Risperidone (risperdal) use

Answer 10

• schizophrenia

- mania

Question 11

Risperidone (risperdal) treats which symptoms

Answer 11

both positive and negative

Question 12

Risperidone (risperdal) MOA

Answer 12

• produce only moderate blockage of dopamine receptor

- stronger blockade for serotonin

Question 13

Risperidone (risperdal) SE

Answer 13

• fewer EPS than first gen
• weight gain
• GI problems

Question 14

Lithium (Lithobid) class

Answer 14

mood stabilizer

Question 15

Lithium (Lithobid) MOA

Answer 15

causes serotonin receptor block

Question 16

Lithium (Lithobid) use

Answer 16

• used to prevent and treat manic episodes in bipolar

- can be used in schizophrenia

Question 17

Lithium (Lithobid) has a

Answer 17

narrow therapeutic index (> 1.5 is toxic)

Question 18

monitor Lithium (Lithobid) levels every

Answer 18

2-3 ddays at initiation and then every 3-6 months

Question 19

Lithium (Lithobid) affects which organs most

Answer 19

RENAL

-those with renal impairment must have dose reduced and serum blood levels carefully monitored

Question 20

Lithium (Lithobid) interactions

Answer 20

do not take diuretics which cause loss of sodium and water (increases lithium tox)

Question 21

Lithium (Lithobid) SE

Answer 21

• tremors
• polyuria
• goiter
• hypothyroidism

Question 22

take what with lithium to prevent GI effect

Answer 22

milk

Question 23

Alprazolam (Xanax) uses

Answer 23

anxiety

Question 24

Alprazolam (Xanax) class

Answer 24

benzodiazepine like diazepam

Question 25

Alprazolam (Xanax) SE

Answer 25

similar to diazepam - CNS depression - vardiovascular collapse, bradycardia, hypotension

Question 26

what to watch for with Alprazolam (Xanax)

Answer 26

CNS depression

Question 27

Buspirone (BuSpar) class

Answer 27

anxiolytic

Question 28

Buspirone (BuSpar) MOA

Answer 28

unclear | it binds to serotonin and dopamine receptors

Question 29

Buspirone (BuSpar) adverse effects

Answer 29

CNS effects | -doesnt potentate the CNS depressants (can take with other benzodiazepine)

Question 30

Buspirone (BuSpar) interactions

Answer 30

- erythromycin - ketoconazole - grapefruit juice

Question 31

when to take Buspirone (BuSpar)

Answer 31

take with meals to prevent gastric irritation

Question 32

Zolpidem (ambien) class

Answer 32

sedative hypnotic

Question 33

Zolpidem (ambien) action

Answer 33

enhances inhibitory effects of GABA inducing sleep

Question 34

Zolpidem (ambien) SE

Answer 34

- drowsiness/dizziness - parasomnias (unusual sleep bahaviors) - anmesia (ambulating, eating driving)

Question 35

when to take Zolpidem (ambien)

Answer 35

admin before bed with 8 hours of possible sleep

Question 36

do not take what with Zolpidem (ambien)

Answer 36

booze or other CNS depressants

Question 37

Amphetamine class

Answer 37

CNS stimulant

Question 38

Amphetamine uses

Answer 38

ADD ADHD narcolepsy

Question 39

Amphetamine risk

Answer 39

high abuse and misuse

Question 40

Amphetamine SE

Answer 40

- psychosis | - cardiovascular

Question 41

Amphetamine abrupt withdrawal equals

Answer 41

abstinence syndrome

Question 42

what to watch with Amphetamine

Answer 42

- BP | - baseline EKG, CBC and platelet

Question 43

Atomoxetine (strattera) class

Answer 43

selective norepinephrine reuptake inhibitor

Question 44

Atomoxetine (strattera) MOA

Answer 44

selective inhibitor of norepi reuptake

Question 45

Atomoxetine (strattera) use

Answer 45

- ADD | - ADHD (children too)

Question 46

Atomoxetine (strattera) adimin

Answer 46

once a day

Question 47

Atomoxetine (strattera) risk?

Answer 47

non stimulant so no potential for abuse

Question 48

Atomoxetine (strattera) adverse effects

Answer 48

- gastrointestional rections - reduced appetitie - dizziness - somnolence - mood swings - trouble sleeping

Question 49

Varenicline (chantix) MO

Answer 49

partial agonist at nicotinic receptors

Question 50

Varenicline (chantix) use

Answer 50

most effective aid for smoking cessation

Question 51

Varenicline (chantix) adverse effects

Answer 51

● Nausea ● sleep disturbances, abnormal dreams ● Constipation, vomiting, dry mouth ● Flatulence ● Potential for serious neuropsychiatric effects (Black box for suicide removed) ● Cardiovascular events (small chance if have underlying disease)