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PHARM > Final: psychotic meds > Flashcards

Final: psychotic meds Flashcards

1
Q

what are the psychotic disorders

A
  • schizophrenia
  • mania
  • acute psychosis
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2
Q

what are positive symptoms of psychotic disorders

A
  • hallucinations
  • delusions
  • racing thoughts
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3
Q

what are the negative symptoms of psychotic disorders

A
  • apathy
  • lack of emotion
  • poor or nonexistant social functioning
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4
Q

how to promote adherence with psychotic disorders

A
  • ensure med is taken
  • encourage family members to oversee med for outpatients
  • use an intramuscular depot prep for long term therapy
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5
Q

Haloperidol (haldol) MOA

A

block receptors for dopamine in the CNS

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6
Q

Haloperidol (haldol) class

A

1st gen antipsychotic

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7
Q

Haloperidol (haldol) use

A
  • schizophrenia
  • acute psychosis
  • tourette’s syndrome
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8
Q

Haloperidol (haldol) SE

A
  • serious movement disorder (extrapyramidal symptoms)
  • neuroendocrine effects
  • prolonged QT interval
  • dysrhythmias
  • sleep problems
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9
Q

Risperidone (risperdal) class

A

2nd gen antipsychotic

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10
Q

Risperidone (risperdal) use

A
  • schizophrenia

- mania

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11
Q

Risperidone (risperdal) treats which symptoms

A

both positive and negative

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12
Q

Risperidone (risperdal) MOA

A
  • produce only moderate blockage of dopamine receptor

- stronger blockade for serotonin

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13
Q

Risperidone (risperdal) SE

A
  • fewer EPS than first gen
  • weight gain
  • GI problems
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14
Q

Lithium (Lithobid) class

A

mood stabilizer

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15
Q

Lithium (Lithobid) MOA

A

causes serotonin receptor block

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16
Q

Lithium (Lithobid) use

A
  • used to prevent and treat manic episodes in bipolar

- can be used in schizophrenia

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17
Q

Lithium (Lithobid) has a

A

narrow therapeutic index (> 1.5 is toxic)

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18
Q

monitor Lithium (Lithobid) levels every

A

2-3 ddays at initiation and then every 3-6 months

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19
Q

Lithium (Lithobid) affects which organs most

A

RENAL

-those with renal impairment must have dose reduced and serum blood levels carefully monitored

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20
Q

Lithium (Lithobid) interactions

A

do not take diuretics which cause loss of sodium and water (increases lithium tox)

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21
Q

Lithium (Lithobid) SE

A
  • tremors
  • polyuria
  • goiter
  • hypothyroidism
22
Q

take what with lithium to prevent GI effect

A

milk

23
Q

Alprazolam (Xanax) uses

A

anxiety

24
Q

Alprazolam (Xanax) class

A

benzodiazepine like diazepam

25
Q

Alprazolam (Xanax) SE

A

similar to diazepam

  • CNS depression
  • vardiovascular collapse, bradycardia, hypotension
26
Q

what to watch for with Alprazolam (Xanax)

A

CNS depression

27
Q

Buspirone (BuSpar) class

A

anxiolytic

28
Q

Buspirone (BuSpar) MOA

A

unclear

it binds to serotonin and dopamine receptors

29
Q

Buspirone (BuSpar) adverse effects

A

CNS effects

-doesnt potentate the CNS depressants (can take with other benzodiazepine)

30
Q

Buspirone (BuSpar) interactions

A
  • erythromycin
  • ketoconazole
  • grapefruit juice
31
Q

when to take Buspirone (BuSpar)

A

take with meals to prevent gastric irritation

32
Q

Zolpidem (ambien) class

A

sedative hypnotic

33
Q

Zolpidem (ambien) action

A

enhances inhibitory effects of GABA inducing sleep

34
Q

Zolpidem (ambien) SE

A
  • drowsiness/dizziness
  • parasomnias (unusual sleep bahaviors)
  • anmesia (ambulating, eating driving)
35
Q

when to take Zolpidem (ambien)

A

admin before bed with 8 hours of possible sleep

36
Q

do not take what with Zolpidem (ambien)

A

booze or other CNS depressants

37
Q

Amphetamine class

A

CNS stimulant

38
Q

Amphetamine uses

A

ADD
ADHD
narcolepsy

39
Q

Amphetamine risk

A

high abuse and misuse

40
Q

Amphetamine SE

A
  • psychosis

- cardiovascular

41
Q

Amphetamine abrupt withdrawal equals

A

abstinence syndrome

42
Q

what to watch with Amphetamine

A
  • BP

- baseline EKG, CBC and platelet

43
Q

Atomoxetine (strattera) class

A

selective norepinephrine reuptake inhibitor

44
Q

Atomoxetine (strattera) MOA

A

selective inhibitor of norepi reuptake

45
Q

Atomoxetine (strattera) use

A
  • ADD

- ADHD (children too)

46
Q

Atomoxetine (strattera) adimin

A

once a day

47
Q

Atomoxetine (strattera) risk?

A

non stimulant so no potential for abuse

48
Q

Atomoxetine (strattera) adverse effects

A
  • gastrointestional rections
  • reduced appetitie
  • dizziness
  • somnolence
  • mood swings
  • trouble sleeping
49
Q

Varenicline (chantix) MO

A

partial agonist at nicotinic receptors

50
Q

Varenicline (chantix) use

A

most effective aid for smoking cessation

51
Q

Varenicline (chantix) adverse effects

A

● Nausea
● sleep disturbances, abnormal dreams
● Constipation, vomiting, dry mouth
● Flatulence
● Potential for serious neuropsychiatric effects (Black box for suicide removed)
● Cardiovascular events (small chance if have underlying disease)

PHARM (15 decks)

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