E2 insulins

Question 1

metformin class

Answer 1

biguanide antidiabetic

Question 2

how does metformin work

Answer 2

reduces production of glucose by liver

Question 3

metaformin does not cause what even in high doses

Answer 3

hypoglycemia

Question 4

can be used alone or with insulin agents

Answer 4

metformin

Question 5

first line med for D2

Answer 5

metformin

Question 6

metformin is what with type 2

Answer 6

weight nutral and ideal for overweight T2 client

Question 7

can be used in children 10+

Answer 7

metformin

Question 8

what needs to be done before metformin is used

Answer 8

renal tests due to large molecule excretion

Question 9

how long before tests with dye does metformin need to be DC

Answer 9

48 hours

Question 10

glyburide (diabeta) class

Answer 10

sulfonylurea

Question 11

how does glyburide (diabeta) work

Answer 11

increases secretion of insulin by stimulating the beta cells to produce more insulin

Question 12

when to take glyburide (diabeta)

Answer 12

30 min before meals

Question 13

glyburide can cause

Answer 13

hypoglycemia

Question 14

glybruide is not recommended for

Answer 14

children and older adults (more sensitive)

Question 15

repaglinide (prandin) class

Answer 15

meglitinide

Question 16

how does repaglinide (prandin) work

Answer 16

stimulates pancreatic secretion of insulin

Question 17

what do you need in order to use repaglinide (prandin)

Answer 17

functioning beta cells

Question 18

when to take repaglinide (prandin)

Answer 18

30 min before meals

Question 19

repaglinide (prandin) can cause what

Answer 19

hypoglycemia

Question 20

repaglinide (prandin) is not recommended for

Answer 20

children

Question 21

pioglitazone (actos) class

Answer 21

thiazolidinedione

Question 22

how does pioglitazone (actos) work

Answer 22

• resensitizes the tissues to insulin (decreases resistance)

- stimulates receptors on muscle, fat and liver cells

Question 23

how long for pioglitazone (actos) to take effect

Answer 23

takes 12 weeks to reach max effect

Question 24

what needs monitored with pioglitazone (actos)

Answer 24

liver enzymes

Question 25

take with meals

Answer 25

pioglitazone (actos)

Question 26

SE with pioglitazone (actos)

Answer 26

fluid retention

Question 27

BBW with pioglitazone (actos)

Answer 27

risk of CHF

Question 28

acarbose (precose) class

Answer 28

alpha-glucosidase inhibitor

Question 29

how does acarbose (precose) work

Answer 29

slows digestion of starces

Question 30

onset for acarbose (precose)

Answer 30

rapid

Question 31

acarbose (precose) works best with

Answer 31

sulfonlyurea

Question 32

can decrease digoxin levels and requires close monitoring

Answer 32

acarbose (precose)

Question 33

when to take acarbose (precose)

Answer 33

take at beginning of meal (first bite)

Question 34

sitagliptin phosphate (januvia) class

Answer 34

DPP-4 inhibitor

Question 35

how does sitaglipitin phosphate (januvia) work

Answer 35

prevents breakdown of incretion that tells pancreas to increase insulin excretion

Question 36

increases insulin production but unlikely to cause hypoglycemia

Answer 36

januvia

Question 37

exenatide (beytta) class

Answer 37

incretin mimetic

Question 38

how does exenatide (beytta) work

Answer 38

acts as natural hormone by stimulating the pancreas to secrete right amt of insulin based on food just eaten

Question 39

SE of exenatide (beytta)

Answer 39

slows gastric emptying

Question 40

how is exenatide (beytta) used

Answer 40

given SQ twice daily within 60 min of morning and evening meal