E3: Heart drugs Flashcards
propranolol drug class
beta blocker
how does propranolol work
blocks beta adrenergic receptors of the sympathetic nervous system
(slows heart rate)
big effect for propranolol
slows heart rate!
what is propranolol used for (5)
- hypertension
- heart failure
- post MI
- angina
- arrhythmias
side effect of propranolol
- depression
- hypoglycemia
- importance
- dizziness
because propranolol is a nonselective beta blocker, what can happen
have effect on B2(lungs)
who is propranolol contraindicated in
people with asthma or other lung disorders
what do you need to check before admin of propranolol
make sure pulse is 60 or greater
captopril (capoten) cass
ACE inhibitor
what is the action of captopril (capoten)
block conversion of angiotensin I to angiotensin II which relaxes vessels and reduces reabsorption of fluid (reducing after load)
captopril (capoten) used for
- HTN
- heart failure
- MI
- Diabetic Nephropathy
most common side effect of captopril (capoten)
unrelenting cough
life threatening side effect of captopril (capoten)
angioedema
other side effects of captopril (capoten) (6)
- Hyperkalemia
- renal failure
- GI distress
- Rash
- Neutropenia
- agranulocytosis
what drug does captopril (capoten) interact with
Digoxin (raises digoxin levels)
captopril (capoten) is contraindicated in who
pregnant people
when to take captopril (capoten)
one hour before meals and two hrs apart from antacids
Losartan (Cozaar) class
angiotensin II receptor blockers (ARB)
action of Losartan (Cozaar)
block angiotensin II causing vasodialatio, reduces volume
SE for Losartan (Cozaar)
- Hyperkalemia
- renal failure
- GI distress
- Rash
- Neutropenia
- agranulocytosis
contraindication for Losartan (Cozaar)
Do not take during pregnancy
when to take Losartan (Cozaar)
may take with food
Verapamil (Calan) class
calcium channel blocker
Verapamil (Calan) action
blocks calcium from cardiac cell reducing contraction, causing vasodialation
Verapamil (Calan) uses (4)
- HTN
- Angina
- Arrhythmias
- circulatory conditions
SE of Verapamil (Calan) (3)
- peripheral edema
- constipation
- suppression of cardiac function (heart block, dysrhy, HF)
Verapamil (Calan) interacts with
grapefruit juice and beta blockers
Nifedipine (Procardia) class
calcium channel blocker
Nifedipine (Procardia) action
blocks calcium from cardiac cell reducing contraction causing vasodialation
Nifedipine (Procardia) uses (4)
- HTN
- angina
- arrhythmias
- circulatory conditions
Nifedipine (Procardia) SE
- peripheral edema
- constipation
Nifedipine (Procardia) interacts with what
- grapefruit
- increased hypotension with beta blockers
Hydralazine (Apresoline) action
direct vasodialation of veins and arteries causing rapid drop in BP
Hydralazine (Apresoline) uses
- severe HTN
- heart failure
Hydralazine (Apresoline) SE (5)
- headache
- dizziness
- edema
- chest apin
- reflex tachy
monitor what with Hydralazine (Apresoline)
BP carefully
Sodium Nitroprusside (Nitropress) action
direct vasodialation of veins and arteries causing rapid drop in BP
Sodium Nitroprusside (Nitropress) uses
hypertensie emergency
risk with Sodium Nitroprusside (Nitropress)
risk of cyanide toxicity
those with liver disorders at an increased risk
Sodium Nitroprusside (Nitropress) SE (5)
- headache
- dizziness
- edema
- chest pain
- reflex tachy
Sodium Nitroprusside (Nitropress) admin
do not admin in a line with any other medication (needs own line)