E2 endocrin Flashcards
(41 cards)
propylthiouracil (PTU) class
anti-thyroid, thionamide
how does propylthiouracil (PTU) work
supresses synthesis of thyroid hormone in hyperthyroidism
propylthiouracil (PTU) dose is dependent on what
metabolism, as thyroid gets under control, less drug is needed
propylthiouracil (PTU) can be what (used)
used alone or with other therapies
propylthiouracil (PTU) is good for who
children who have greater risks with radioactive iodine
propylthiouracil (PTU) is not preferred for who
older adults
BBW for propylthiouracil (PTU)
severe liver injury resulting in death or acute liver failure
propylthiouracil (PTU) adverse effects
- hypothyrodism
- agranulocytosis-
- derma effects
- CNS effects
- GI effects
levothyroxine use
choice drug for long term treatment of hypothyroidism
levothyroxine is what kind of therapy
life long with medical supervision needed
you cannot just stop levothyroxine abruptly
duh
adverse effects with levothyroxine
- s/s of hyperthyroidism
- tachy
- dys
- fractures from bone loss
dosage with levothyroxine needs to be what
individualized
when to take levothyroxine and what before
on empty stomach in the AM and take pulse before
what to watch for with levothyroxine
thyroidtoxicosis
somatropin use
used in kids whos growth is impaired by deficiency of endrogenous GH
how does somatropin work
stimulates skeletal, linear, muscle, organ grown
how is somatropin given
SQ or IM
adverse effects of somatropin
not common
-fewer in kids
somatropin decreases what
insulin sensitivity resulting in hyperglycemia
somatropin interacts with what
glucocorticoids (dont take at same time)
desmopressin (DDAVP) class
posterior pituitary hormone
desmopressin (DDAVP) use
diabetes insipidus
how is desmopressin (DDAVP) given
oral, intranasal, IV
