final exam 2 Flashcards
staphylococcus, streptococcus, bacillus, enterococcus, and clostridium are
gram +
gram positive disease is mostly from secreted
toxins
low amt of guanine-cytosine nucleotide base pairs versus adenin thymine nucleotide pairs
low G and C bacteria
high amount of guanine cytosine nucleotide base pairs versus adenine-thymine nucleotide base pairs
high g and c bacteria
prefer to grow in environments with oxygen for aerobic respiration but can grow and survive in environments without oxygen
facultative anaerobe
lack flagella
non-motile
which of staph is the most virulent strain
staph aureus
normal microbiotoa of the human skin but can cause opportunistic infections in very rare cases
staph epidermidis
what agar is used to identify between staph
MSA
which staph ferments mannitol
aureus and changes it to yellow
when is infection resulted in for stpah
when it breaches skin or mucous membrane to reach blood
extracellular enzymes of staph
cell-free coagulase, staphylokinase, hyaluronidase, lipases, and b-lactamase
reacts with prothrombin causing the inactive fibrinogen to convert to the active fibrin
cell free coagulase
dissolves fibrin causing blood clots to breakdown or dissolve
staphylokinase
this enzyme allows bacteria to pass between cells in the epidermis by breaking hyaluronic acid
hyaluronidase
breaks down lipids and oil for energy on the skin allowing staphylococci to grow on surface of skin and in cutaneous oil glands
lipases
gives antibiotic resistance as this enzyme breaks open and destroys beta lactam ring found in all beta lactam antibiotics such as penecillin
b-lactamase
binds to antibodies blocking the location where phagocytes grab onto the antibodies during phagocytosis
protein A
inhibit leukocyte chemotaxis and phagocytosis
slime layer
binds and weakens or destroys the plasma membrane
cytolytic toxin
specifically find to and destroy all leukocytes
leukocidin toxin
breakdown desmosomes causing skin cells to separate and slough off
exfoliative toxins
stimulate intestinal contraction nausea and intestine vomitting
enterotoxins
study of incidience, distribution and control of disease
epidemiology
which staph is found everywhere on human skin
staph epidermidis
which staph is only found on moist skin folds
staph aureus
staph grows in
UR, GI and urogenital tracts
how is staph transmitted
direct contact or fomites