chapter 15 Flashcards
what line of defense is the external, physical barrier of the human body
first line
what does the first line of defense include
mucous membranes that line the respiratory, digestive, urinary, and reproductive tracts
what line of defense is the internal and bloodborne part of the human body
second line
does the second line include lymphocytes
no
what is second line composed of
protective cells, leukocytes, bloodborne chemicals
an immune response that is always on, responds rapidly to pathogens and is broad spectrum
innate immunity
what is the third line of defense called
adaptive immune system
what makes up the third line
lymphatic system and lymphocytes
two layers of the skin
superficial epidermis and deep dermis
what makes up the bottom layer of the cells in the epidermis
stratum basale
which portion of skin contains blood supply and nutrients
dermis
fibrous thick protein of the skin
keratin
cells in the epidermis are called
keratinocytes
possible written question
what are the characteristics of the epidermis
- tightly packed cells
- top layer of cells are dead
- dry - lack of moisture or water
- keratinized
- slough off or fall off easily
long, slender fingers that extend to surrounding cells, play a role in phagocytosis and can activate the adaptive immune system
dendritic cells
what makes the dermis tissue physically strong and flexible
collagen
dermis tissue secretes
perspiration which ocntains salt, lysozome, and antimicrobial peptides
causes sweat to acts as a hypertonic solution that dries out and shrinks pathogens
salt
an enzyme that cleaves the linkages between sufars in the cell walls of bacteria
lysozome
what does lysozome do
destructs the cell wall leads to death by osmotic pressure
a group of antimicrobial peptides that are secreted by the sweat galnds, broad spectrum that kill bacteria and fungi
dermcidins
how do dermcidins kill bacteria
poke hols in the cell membrane which allows vital chemicals to leak out
secreted from sebaceous or oil glands which softens skin making it more flexible and less likely to break down
sebum
sebum contains what which does what
contains fatty acids, lowers skin ph below 5 which inhibits growth and metabolism of pathogens
line all body cavities open to the environment, thin and moist compared to skin
mucous membrane
two layers of the mucous membrane
epithelium and deep connective layer
very thin layer that is closest to the lumen
epithelium
a thick layer of connective tissue that provides mechanical and nutritional support to the epithelium
deep connective layer
characteristics of the epithelium
- cells are alive and moist - both water an nutrients present
- tightly packed cells
- continual shedding of cells
- cells are ciliated columnar cells
secrete sticky thick mucous to trap pathogens and cilia can move out of body or into GI tract
goblet cells