Final Flashcards
superior
above, toward head
proximal
toward point of attachment
medial
toward midline
lateral
away from midline
distal
away from point of attachment
inferior
below, toward feet
cranial
toward head
posterior
back
anterior
front
caudal
toward tail
thoracic cavity contains
heart and lungs. boundaries are established by chest wall and diaphragm
abdominopelvic cavity contains
encloses the peritoneal cavity.
abdominal cavity: digestive glands and organs
pelvic cavity: urinary bladder, reproductive organs and last portion of digestive tract
homeostasis
presence of of a stable internal environment
initial stimulus produces a response that exaggerates the change in the orginal conditions
postitive feedback
an effector activated by the control center opposes or negates the original stimulus, minimizes change
negative feedback
dehydration synthesis
forms a complex molecule by removing a water molecule
hydrolysis:
one of the bonds in a complex molecule is broken and the components of a water molecule are added to resulting fragment
peroxisome
breakdown of organic compounds
lysosomes
breakdown of organic compounds and damaged organelles
microvilli
increase surface area to facilitate absorption
Golgi apparatus
stores, alters, and packages synthesized products
ER
synthesis of secretory products
smooth: synthesizes lipids and carbohydrates
rough: modifies and packages proteins
ribosomes
protein synthesizes
mitochondria
produces 95% of ATP required by the cell
cytoskeleton
strengthens and supports the cell
Isotonic solution
does not cause an osmotic flow of water into to out of cell
hypotonic solution
causes osmotic water flow into the cell. swell and burst
hypertonic solution
in osmotic movement of water out of cell. cell shriveled and dehydrates
diffusion of water molecules across a selectively permeable membrane. high to low
osmosis
passively transported across plasma membrane. No ATP required
facilitated diffusion
provides the energy needed to move ions or molecules across the plasma membrane. not dependent on concentration gradient. 3 Na+ ions and 2 K- ions
active transport
materials move into or out of cell in vesicles
vesicular transport
importing extracellular substances through the formation of vesicles at the bell surface
endocytosis
produces vesicles containing a specific target molecule
receptor-mediated
formation of endoscopes filled with extracellular fluid
pinocytosis
cell eating
phagocytosis
vesicle formed inside the cell fuses with and becomes part of plasma membrane
exocytosis
epithelial tissue
provide physical protection, control permeability, provide sensation, produce specialized secretions
hemidesosomes
attach deepest epithelial cells to basement membrane
tight junctions
between wo plasma membranes, intestinal tracts
gap junctions
allow for rapid communication. found in heart
demosomes
glue , provide firm attachment
cartilage
matrix is a firm gel of chondroitin sulfates and protein substances. shock absorption and protection. chondrocytes. no blood vessels
bone
small vol. of ground substance. matrix made u[ of calcium slats. provide flexibility, tons of blood vessels
skeletal muscle tissue
moves the body
smooth muscle tissue
moves fluids and solids along digestive tract
cardiac muscle tissue
found in the heart
functions of the integumentary system
protect underlying tissues and organs & maintain body temperature
rickets
condition that results in flexible, poorly mineralized bones
layers of epidermis: straum basale
deepest layer of epidermis, attached by hemidesomsones
layers of epidermis: stratum spinosm
spiny layer
layers of epidermis: stratum granulosm
grainy layer, cells stop dividing and start producing keratin
layers of epidermis: stratum lucidium
clear layer, only in thick skin
layers of epidermis: stratum corneum
horn layer, exposed to surface to skin
dermis =
2 layers
papillary layer:
composed or areolar tissue. contains: smaller capillaries, lympathic vessels and sensory neurons. dermatitis
reticular layer
interwoven meshwork of dense irregular connective tissue with collagen and elastic fibers. larger blood vessels. all cells of connective tissue present
cyanosis
blue
lack of oxygen or blood flow
jaundice
yellow
build up of bile in the liver
pituitary tumor
darkening of skin
excess of MSH
Addisons disease
skin darkening
disease of pituatry gland
vitiligo
loss of color, loss of melanocytes
repair of skin process
- inflammatory; intial injury causes bleeding and mast cell activation
- migratory: blood clot (scab) forms. migrate down rapid cell divison and migration along wound edges o replace missing cells
- proliferation: fibroblast have formed collagen fibers and ground substance
- scarring: scab sheds, epidermis complete. fibroblast continue to make scar tissue
flat bones
thin w/ parallel surface
skull bones, sternum, ribs, scapulae
sutural bones
small, irregular bones
found btw flat bones of the skull
long bones
relatively long and thin
arms, legs, hands, feet, fingers and toes
irregular bones
have complex shapes
vertrebrae, bones of pelvis facial bones
seasomid bones
small and flat
develop inside tendons near joints of knees, hands, and feet
short bones
small boxy/ thick
bones of wrist and ankles
epiphysis
wide part, ends of long bone, spongy bone, covered with articualar cartilage
diaphysis
the shaft, heavy wall of compact bone, central space= medullary cavity
metaphysis
epiphysis and diaphysis meet
endochondral ossification
ossifes bone that orginate as hyaline cartilage
- primary ossification center: begin spongy bone production. start to add to matrix, in center of diaphysis .
- meduallry cavity: moving toward the epiphysis
- secondary ossification center: capillaries and osteoblast migrate toward epiphysis
- at puberty, closes off (epiphysiseal line)
intramembranous ossification
occurs in the deeper layer of dermis
osteogenic cells
divide to produce daughter cells that differinate into osteoblast
osteoblast
make and release proteins. produce new bone matrix in ossificatoin
osteocytes
mature bone cells that maintain bone matrix
osteoclast
remove bone matrix
factors that increase blood calcium level
- triggered when falls below 8.5 mg/dL
- cells of the parathyroid hormone gland release parathyroid hormone into blood stream
- bone cells: release calcium
- kidneys: increase calcitriol, calcium conserved
- intestines: calcium absorbed qucikly
factors that decrease blood calcium level
-triggered when above 11 mg/dL
- C cells in thyroid gland secret calcitonin
- bone : calcitonin descrease osteoclast, calcium release slowed
- intestinal: calcium abosrbed slowly
- kidney: supresses calcium ion reabsorption, calcium excreted
cervical
7, supports weight of head
thoracic
12, each one slightly larger, able to bear increasing weight
lumbar
5, thick body than the thoracic vertebrae
liagment
bone to bone
support and strengthen joints
tendon
muscle to bone
help support joint
dynamic motions
linear movement (gliding), angular movement, circumduction, rotation
angular motions
flexion, extenstion, hyperextenstion, lateral flexion, dorsiflexion, plantar flexion, abduction, adduction
rotation
pronation and supination
special
oppostion, inversion, eversion, protraction, retraction, elevation, depression
annulus fiborus
tough outer ring of fibrocartilage
nucleus pulpous
soft, elastic, gelatnious core
skeletal muscle function
produce body movement, maintain posture, support, guard, maintain body temp, store
sacromere
A bands: dark, thick filaments - M line: center of A band -H band: area around M line -zone of overlap I band: light, thin filaments -Z lines: center of I bands @ 2 ends -titin: strands of elastic protein
f-actin
holf the active sites which will bind to myosin
nebulin
holds the f-actin together
tropomyosin
covers active sites
troponin
globular protein that binds to tropomyosin, controlled by Ca2+
initating a muscle contraction
- Ca2+ bind to receptor on troponin
- Tropoin will cause tropomypsin to move out of the way and expose active sites on f-actin so active site can bind with myosin head
sliding fliament theory
- skeletal muscle contracts, thin slide past thick.
- H bands and I bands get smaller, the zones of overlap get larger, Z lines move closer together and width of A stays the same
sacrolemma
plasma membrane of muscle fibers, surrounds sacroplasm
T-tubules
transmit the action potential through the cell, allowing entire muscle fiber to contract
thin=
actin
thick=
myosin
SR
help transmit the action potential to the myofibril. terminal cisternae. 1 T-tubule, 2 terminal cisternae
contraction cycle
- resting sacromere: mysoin heads all energized and cocked.
- contraction cycle begins: begins with arrival of calicum from SR to zone of overlap
- Active Site exposure: Ca binds to troponin which moves tropomyosin out of the way exposing active sites
- Cross-bridge formation: once active site exposed, energized myosin heads bind to them forming cross-bridges
- Myosin head pivoting: pivots toward M line, called power stroke. happens when ADP and P released
- Cross bridge detachment: new ATP attach to myosin head, releases from actin. active site avaliable to form another cross bridge
- Myosin reactivation: myosin head is reactivated when the ATP splits into ADP and P.
Isotonic
tension: same
length: changes
Isometric:
tension: changes
length: same
Anaerobic:
no oxygen
glycolysis, 2 ATP produced
Aerobic
oxygen required
Mitochondria, 38 ATP produced
CNS
brain and spinal cord.
process and coordinate sensory data, motor commands, and higher functions
PNS
all nervous tissue outside CNS, deliver sensory info to the CNS and carry motor commands
Afferent
carries sensory info from PNS to CNS
Efferent
carries motor commands from CNS to PNS msucles and galnds
Autonomic
parasympatheic and sympatheic
All or none principle
given stimulus githr triggers a typical action potential or triggers none at all
continous propgation
+30 mV
- action potential develops @ intial segment, depolarizes at 30 mV
- sodium ions entering @intial segment spread away from open voltage-gated chanels, a graded depolarization quickly, brings 2 threshold
- begins repolarization
- Na ions enter segment 2, graded depolarization quickly brings the membrane in seg 3 to threshold. only move foward not backward
salvatory propagnation
much faster
white matter of spinal cord
superifical, myelinated and unmyelinated
gray matter of spinal cord
deep, forms butterfly shape. unmyelinated. cerbrospinal fluid
posterior median sulcus
shallow, longitudal groove on posterior surface
anterior median fissure
deep groove on anterior surface
spinal meninges functions
phyiscal stability and shock absorption
spinal meninges dura matter:
outermost. tough. epidural space
spinal meninges arachnoid matter
middle. subdural: btw arachnoid and dura. subarachnoid: btw arachnoid and pia. filled with CSF
spinal meninges pia matter
intermost
gray horns posterior
somatic and visceral
gray horns lateral
visceral
gray horns anterior
somatic
gray commissures
contain axons that cross from side to side on spinal cord
posterior white columns
btw posterior gray horn and median sulcus
lateral white column
btw anterior and posterior
anterior white column
btw anterior gray horns
white commissure
interconnects anterior white columns, axons cross side to side
ascending tracts
posterior columns, sensory information
descending tracts
anterior, motor commands
There are _____ spinal cord segments
31
phenic nerve
provides entire nerve supply for diaphragm
sciatic
largest/ longest nerve in body, sacral
monosynaptic
one synapse, stretch reflex. patellar reflex. receptor is muscle spindle
polysnpatic
multiple synapse. more complicated. interneurons will control more than 1 muscle group. withdraw reflex. flexot reflex
cross extenstor
affect other side of body
cerebrum
conscious thought, memory storage and processing sensory info
diencephalon
thalamus and hypothalamus
thalamus: relay and procesing centers for sensory info
hypothalamus: emotions, autonomic function and hormone function
midbrain
process visual and audiotry info and control relexes
pons
connects cerebellum to the brainstem
medulla oblongata
relays sensory info to portions o brainstem and to the thalamus. heart rate, BP, digestion
ventricles are filled with
CSF
lateral ventricle
very large, interventricular foramen connects lateral to the 3rd
3rd ventricle
diencephalon, cerebrual aqueduct (3rd to 4th)
4th ventricle
extends into upper part and medulla oblongata, central canal
craninal meninges dura matter
no epidural space
craninal meninges arachnoid space
membrane: closest to dura matter
trabeculae: connects to pia matter
craninal meninges pia matter
astrocyte process
choroid plexus
secrete CSF into ventricles
BBB
isolates CNS neural tissues from general circulaton. formed by tight junctions. astrocytes
cerebellum contains what cells
purkinjie
cerbral cortex
conscious thought, memory, sensory
frontal lobe
voluntary movement, sensory, speech
parietal lobe
touch, pressure, pain, vibration or temp
occipital lobe
vision
temporal lobe
sound
left hemisphere
math and reading
right hemisphere
analyzes
corpus callosum
allows communication and coordinate to left and right hemispheres
cranial nerve 1
Olfactory, somatic
cranial nerve 2
optic, somatic
cranial nerve 3
oculomotor, motor
cranial nerve 4
trochelar, motor
cranial nerve 5
trigeminal, both
craninl nerve 6
abducens, motor
craninal nerve 7
facial, both
cranial nerve 8
vestiobucholear, somatic
cranial nerve 9
vagus, both
cranial nerve 10
accessory, both
cranial nerve 11
hyopglossal, motor
bells palsy
cranial nerve disorder from inflammation to facial nerve
nociceptors
pain
thermoreceptors
temp. adapt quickly
proprioceptors
monitor positions at joints and muscles
baroceptors
monitor pressure
tactile recpetors
touch, pressure, and vibration
1st order neuron
enter spinal cord and syanpse on second order neuron within the posterior gray horns
2nd order neurons
cross opposite side of spinal cord before ascending to thalamus
3rd order neurons
synapse in primary somatic sensory cortex
posterior column pathway
sesnations of high localized touch , pressure, vibrations
spinocerebellar
propriocpetive info
spinothalmic
conscious sensations of poorly localized
corticospinal pathway
provides voluntary control over skeletal muscles
sympathetic
- pregangolnic synapse:
- preganglionic fibers:
- postganglionic:
- location:
- in ganglia near spinal cord
- short
- long
- T1-L2
parasympathetic
- preganglionic synapse:
- preganglionic fibers:
- postganglionic:
- location:
- in gangila near target organs
- long
- short
- craino-sacral
collection of neuron cell bodies in PNS. innervate visceral effectors such as cardiac muscle muscle, smooth muscle, glands, adipose tissue
ganglia
oversees body functions
vagus
alpha receptors
activates G proteins on cytoplasmic side of plasma membrane
beta recpetors
located on plasma membrane of cells in many organs
motor neurons that maintain a contnious level of spontanoeus activity
autonomic tone
how does the body absorb calcium
absorbed through the lining of the small intestine into the bloodstream.