Chapter 5 Flashcards
The integument system is made of 2 parts:
cutaneous membrane and accessory structures
What is in the cutaneous membrane?
epidermis and dermis
composed of stratified squamous epithelium
epidermis
Papillary layer (areolar connective tissue), reticular layer (dense irregular connective tissue)
dermis
originate in the dermis, extend through the epidermis to the surface
accessory structures
where do accessory structures originate
dermis
examples of accessory structures
nails, hair, exocrine glands
network of blood vessels
cutaneous plexus
separates integument from deep fascia, not part of integument
subcutaneous layer (hypodermis)
what are the functions of the skin?
- protection of underlying tissues and organs
- excretion of salts, water, and organic waste
- maintenance of body temperature
- production of melanin
- synthesis of vitamin d3
- production of keratin
- storage of lipids in dermis and subcutaneous layer
- detection of touch, pressure, pain, and temperature
What is the primary cell type of the epidermis?
keratinocyte
Entire epidermis lacks what?
blood vessels. cells get oxygen from capillaries in the dermis
How many days does it take for a cell to move from the deepest statrum to most superficial layer?
7-10 days
The deepest layers of epidermis, adjacent to dermal papillae, function is to increase surface area for better attachment
epidermal ridges
Thin skin has __ layers
4
Thick skin has __ layers.
5
Thick skin covers what parts of the body?
palms of hands and soles of feet
deepest layer of strata. attached to basement membrane by hemidesmosomes. forms a strong bond between epidermis and dermis. most cells are basal cells- stem cells that divide to replace more superficial cells
stratum basale (5 layer)
The spiny layer of stratum. produced by division of stratum basal. 8-10 layers of keratinocytes bound by demsomsomes. Cells shrink until cytoskeleton stick out (spiny). continue to divide, increasing the thickness of epithelium
stratum spinosum (4th layer)
The grainy layer of stratum. cells stop dividing and start producing keratin and keratohylain
stratum granulosm (3rd layer)
The “clear” layer”. found only in thick skin
stratum lucidum (2nd)
The horn layer of stratum. exposed surface of skin. 15-30 kertainzed cells. Water resistant
stratum corneum (1st)
The formation of layer of dead, protective cells filled with kerati. occurs on all exposed skin surfaces except eyes
keratinization
How long before cells are shed or washed away
2 weeks
Skin color is influenced by
presence of pigments, blood circulation, thickness and degree of kertinazation in epidermis, exposure to UV radiation
Color: brown, yellow-brown, or black pigment.
Produced by: melanocytes in stratum basale
Stored in: melanocytes
Transfered to: keratinocytes
Malanin
Color: orange- yellow pigment
Found in: orange vegetables
Accumulates in epidermal cells and fatty tissues of the dermis
Can converted to Vitamin A
Carotene
Type of skin cancer that stays in the epidermis. Most common form of skin cancer . Orginates in stratum basale due to mutations caused by overexposure to UV radiation.
Basal cell carcinoma
Type of skin cancer where melanocytes are more intricately connected to the connective tissue so that is why it often spreads and is more fatal. Extremely dangerous, grow rapidly and metastatasize through lymphatic system
Melanoma
How to detect skin cancer?
A- asymmetry B- border C- color D- diameter E- evolving
what are the functions of melanocytes?
protect skin from skin damage
skin color depends on melanin _________, not on the number of melanocytes
production
_________ is red pigment found in red blood cells
hemoglobin
blood vessels dilated from heat =
skin reddens
blood flow decreases =
skin pales
Caused by severe reduction in blood flow or oxygenation, bluish skin tint
cyanosis
buildup of bile produces by liver, yellow
jaundice
excess MSH, darkening of skin occurs, deep bronze
pituitary tumor
a disease of the pituitary gland, skin darkening
Addisons disease