Final 3!!!

Question 1

Analgesic
Antipyretic

Answer 1

dec pain
dec fever

Question 2

Aspirin daily dosages
Low?
Medium?
High?

Primary Uses?

Answer 2

Low (75-81mg/day) for antiplatelet
Medium (650-4000 mg/day) antipyretic and analgesic
High (4000-8000 mg/day) antiinflammation

antiplatelet

Question 3

Aspirin
ADR

Answer 3

GI ulcers, impaired kidney function
NO for kids

Question 4

NSAID
1st gen

Answer 4

Naproxen - otc
Indomethacin
Ketoprofen -otc
Etodolac
Ketorolac - potent af
Ibuprofen - ot

Question 5

Which NSAIDs are OTC? 3

Answer 5

ibuprofen
naproxen
ketoprofen

Question 6

Agents:
Uses:
ADR: increased risk of cardiac events

Answer 6

Celecoxib
Meloxicam (partial)
decreases risk of ulcers bc no COX 1 inhibition
increased risk of cardiac events

Question 7

Acetaminophen
Uses:
Dose:
ADR:

Answer 7

analgesic and antipyreticDose:
Acute: 4g
Chronic: 3g
Hepatic impairment: 2g
ADR: can cause hepatotoxicity

Question 8

Full agonists:

Answer 8

Full agonists:
Morphine
Meperidine
Methadone
Fentanyl strongest
Oxycodone
Codeine
Hydrocodone

Question 9

Naloxone
Naltrexon

Answer 9

It can treat narcotic overdose in an emergency situation

Question 10

Opioid ADR

Answer 10

Constipation - most common
Respiratory depression - most serious
Drowsiness
Itching - parenteral
N/V

Question 11

Hyperglycemia symptoms
Polyuria

Drinking lots that’s why pee a lots?
or pee lots that’s why drinking a lots?

Answer 11

Pee lots that’s why drinking a lots.

Question 12

What is the function of insulin?

Answer 12

Insulin is a hormone that lowers the level of glucose (a type of sugar) in the blood

Question 13

Sulfonylureas
agents

Answer 13

most effective class
Glyburide
Glipizide
Glimepiride

Question 14

Glyburide
Note

Answer 14

Sulfonylureas
ataking in the morening
becomes less effective overtime

Question 15

Meglitinides
agents

Answer 15

Repaglinide
Nateglinide
“glinide”

Question 16

Meglitinides

Answer 16

must skip med if skip meal
take before meal

Question 17

Insulin sensitizer
Biguanides
agent

Answer 17

Biguanides: other most effective class
metformin

Question 18

metformin
ADR
BBW!!

Answer 18

no hypoglycemia or weight gain
Lactic acidosis
contraindicated in reduced kidney function

Question 19

Thiazolidinediones (TZDs)
agent

Answer 19

Pioglitazone
Posiglitazone
“glitazone”

Question 20

Pioglitazone
ADR
BBW!!

Answer 20

increase ovulation
severe heart failure

Question 21

SGCT 2 inhibitor:
Agents:

Answer 21

Canagliflozin
Dapagliflozin
Empagliflozin
“gliflozin”

Question 22

Canagliflozin
a) ADR
b) BBW!

Answer 22

a): no risk of hypoglycemia, contraindicated in renal impairment
Makes u pee out glucose
b) diabetic foot ulcers and amputation

Question 23

DPP-4 inhibitors
agents
ADR

Answer 23

Alogliptin
Sitagliptin
Saxagliptin
Linagliptin
“gliptin”
Facial edema

Question 24

GLP-1 agonists meds
agent

Answer 24

pramilintide
(amylinomimetic)
“tide”

Question 25

pramilintide BBW

Answer 25

thyroid tumors in rats (liraglutide, exenatide XR) Improves beta cell function

Question 26

Basal insulin? Bolus insulin?

Answer 26

Provide consistent insulin level to decrease blood glucose Moring to night/ long acting Administer to decrease glucose after meal Rapid or short acting

Question 27

Basal insulin? Bolus insulin?

Answer 27

a)Provide consistent insulin level to decrease blood glucose **give at night** b)Administer to decrease glucose after meal Rapid or short acting **give between meals**